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SEPHS1 Antibody

  • 货号：
    CSB-PA021015ESR2HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Western blot
      All lanes: SEPHS1 antibody at 3.05μg/ml
      Lane 1: Mouse liver tissue
      Lane 2: HepG2 whole cell lysate
      Lane 3: Mouse kidney tissue
      Lane 4: U251 whole cell lysate
      Secondary
      Goat polyclonal to rabbit IgG at 1/10000 dilution
      Predicted band size: 43, 36 kDa
      Observed band size: 43 kDa
    • Immunohistochemistry of paraffin-embedded human colon cancer using CSB-PA021015ESR2HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human lung cancer using CSB-PA021015ESR2HU at dilution of 1:100
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) SEPHS1 Polyclonal antibody
  • Uniprot No.：
    P49903
  • 基因名：
    SEPHS1
  • 别名：
    SEPHS1 antibody; SELD antibody; SPS antibody; SPS1 antibody; Selenide antibody; water dikinase 1 antibody; EC 2.7.9.3 antibody; Selenium donor protein 1 antibody; Selenophosphate synthase 1 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human, Mouse
  • 免疫原：
    Recombinant Human Selenide, water dikinase 1 protein (1-392AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity Purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, WB, IHC
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:1000-1:5000
    IHC 1:20-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Synthesizes selenophosphate from selenide and ATP.
  • 基因功能参考文献：
    1. Three SNPs in SEPSECS and SEPHS1 were found to significantly interact with serum selenium level and Crohn's Disease. PMID: 23112913
    2. Five alternative splice variants of human SPS1 (major type, DeltaE2, DeltaE8, +E9, +E9a) were identified wherein +E9 and +E9a make the same protein. PMID: 20471958
    3. Sps1 affect cell viability upon ionizing radiation via modulation of p53 activity. Sps1 and its product selenophosphate might be involved in cancer prevention in a p53-dependent manner and could be applied to development of a novel cancer therapy. PMID: 16786570
  • 亚细胞定位：
    [Isoform 1]: Cell membrane; Peripheral membrane protein. Nucleus membrane; Peripheral membrane protein.; [Isoform 2]: Cytoplasm.; [Isoform 3]: Cytoplasm.; [Isoform 4]: Cytoplasm.
  • 蛋白家族：
    Selenophosphate synthase 1 family, Class II subfamily
  • 组织特异性：
    [Isoform 1]: Gradually expressed during the cell cycle until G2/M phase and then decreases.; [Isoform 2]: Gradually expressed during the cell cycle until G2/M phase and then decreases.; [Isoform 3]: Gradually expressed during the cell cycle until S phase
  • 数据库链接：

    HGNC: 19685

    OMIM: 600902

    KEGG: hsa:22929

    STRING: 9606.ENSP00000367893

    UniGene: Hs.124027