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SEZ6L2 Antibody

  • 货号：
    CSB-PA761499LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Immunofluorescence staining of MCF-7 cells with CSB-PA761499LA01HU at 1:133, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
  • 其他：

产品详情

  • 产品名称：
    Seizure 6-like protein 2 anti-Homo sapiens (Human) SEZ6L2 Polyclonal antibody
  • Uniprot No.：
    Q6UXD5
  • 基因名：
    SEZ6L2
  • 别名：
    SEZ6L2 antibody; PSK antibody; UNQ1903/PRO4349 antibody; Seizure 6-like protein 2 antibody
  • 宿主：
    Seizure 6-like protein 2
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human Seizure 6-like protein 2 protein (28-372aa)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，SEZ6L2 Antibody (CSB-PA761499LA01HU)，的标记方式是Non-conjugated。对于SEZ6L2 Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA761499LB01HU SEZ6L2 Antibody, HRP conjugated ELISA
    FITC CSB-PA761499LC01HU SEZ6L2 Antibody, FITC conjugated
    Biotin CSB-PA761499LD01HU SEZ6L2 Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Antigen Affinity purified & Affinity purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, IF
  • 推荐稀释比：
    Application Recommended Dilution
    IF 1:50-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    May contribute to specialized endoplasmic reticulum functions in neurons.
  • 基因功能参考文献：
    1. SEZ6L2 can partially correct the cathepsin D hypersecretion. PMID: 26698217
    2. These results provide an extensive ascertainment of the genetic variability of SEZ6L2 in human populations and do not support a major role for SEZ6L2 sequence variations in the susceptibility to autism spectrum disorders. PMID: 21394203
    3. significant association between autism and a coding variant in the seizure-related gene SEZ6L2 gene; SEZ6L2 expression in human fetal brain was highest in post-mitotic cortical layers, hippocampus, amygdala, and thalamus PMID: 19242545
  • 亚细胞定位：
    Cell membrane; Single-pass type I membrane protein. Endoplasmic reticulum membrane; Single-pass type I membrane protein. Note=Detected on cell surface of lung-cancer.
  • 蛋白家族：
    SEZ6 family
  • 数据库链接：

    HGNC: 30844

    OMIM: 616667

    KEGG: hsa:26470

    STRING: 9606.ENSP00000312550

    UniGene: Hs.6314