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SGSM3 Antibody

  • 货号：
    CSB-PA021203GA01HU
  • 规格：
    ￥3,900
  • 其他：

产品详情

  • Uniprot No.：
    Q96HU1
  • 基因名：
    SGSM3
  • 别名：
    Bdif 1 antibody; Cip85 antibody; Cx43 interacting protein of 85 kDa antibody; MAP antibody; Merlin associated protein antibody; merlin binding protein antibody; Merlin-associated protein antibody; R75178 antibody; rab GTPase activating protein like protein antibody; Rab-GTPase-activating protein-like protein antibody; RABGAP5 antibody; rabGAPLP antibody; RUN and SH3 containing 3 antibody; RUN and TBC1 domain containing 3 antibody; RUN and TBC1 domain containing protein 3 antibody; RUN and TBC1 domain-containing protein 3 antibody; RUN and TBC1 domains-containing protein 3 antibody; RUSC3 antibody; RUTBC3 antibody; SGSM3 antibody; SGSM3_HUMAN antibody; Small G protein signaling modulator 3 antibody; Small G protein signaling modulator 3 protein antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse,Rat
  • 免疫原：
    Human SGSM3
  • 免疫原种属：
    Homo sapiens (Human)
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,WB,IHC,IF
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    May play a cooperative role in NF2-mediated growth suppression of cells.
  • 基因功能参考文献：
    1. SGSM3 gene polymorphism is associated with the risk of breast cancer in Chinese population. PMID: 27432265
    2. The CIP85 was observed to interact with clathrin, which suggested a role for CIP85 in the clathrin-mediated internalization of Cx43. PMID: 23586710
    3. rs56228771 may contribute to hepatocarcinogenesis, possibly by affecting SGSM3 expression through a miRNA-mediated regulation. PMID: 23918301
    4. MAP decreased the AP-1-dependent promoter activity additively with merlin in NIH3T3 cells.Results suggest that MAP may play a cooperative role in the merlin-mediated growth suppression of cells. PMID: 15541357
    5. Identification of novel protein SGSM3 which modulates small G protein (RAP and RAB)-mediated signaling pathway. PMID: 17509819

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  • 亚细胞定位：
    Cytoplasm.
  • 蛋白家族：
    Small G protein signaling modulator family
  • 组织特异性：
    Widely expressed.
  • 数据库链接：

    HGNC: 25228

    OMIM: 610440

    KEGG: hsa:27352

    STRING: 9606.ENSP00000248929

    UniGene: Hs.474914