Your Good Partner in Biology Research

  1. Home
  2. 抗体
  3. 多克隆抗体
  4. SIRPB1 Antibody

SIRPB1 Antibody

  • 货号：
    CSB-PA021335LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Immunohistochemistry of paraffin-embedded human thyroid tissue using CSB-PA021335LA01HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human colon cancer using CSB-PA021335LA01HU at dilution of 1:100
    • Immunofluorescent analysis of Hela cells using CSB-PA021335LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
    • Western Blot
      Positive WB detected in: THP-1 whole cell lysate , A549 whole cell lysate , PC-3whole cell lysate , JK whole cell lysate ,mouse heart tissue lysate
      All lanes: SIRPB1 antibody at 1:1000
      Secondary
      Goat polyclonal to rabbit IgG at 1/50000 dilution
      Predicted band size: 44 kDa
      Observed band size: 44 kDa
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) SIRPB1 Polyclonal antibody
  • Uniprot No.：
    O00241
  • 基因名：
  • 别名：
    SIRPB1 antibody; Signal-regulatory protein beta-1 antibody; SIRP-beta-1 antibody; CD172 antigen-like family member B antibody; CD antigen CD172b antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human, Mouse
  • 免疫原：
    Recombinant Human Signal-regulatory protein beta-1 protein (30-371AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，SIRPB1 Antibody (CSB-PA021335LA01HU)，的标记方式是Non-conjugated。对于SIRPB1 Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA021335LB01HU SIRPB1 Antibody, HRP conjugated ELISA
    FITC CSB-PA021335LC01HU SIRPB1 Antibody, FITC conjugated
    Biotin CSB-PA021335LD01HU SIRPB1 Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, WB, IHC, IF
  • 推荐稀释比：
    Application Recommended Dilution
    WB 500-2000
    IHC 1:20-1:200
    IF 1:50-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Immunoglobulin-like cell surface receptor involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes. Participates also in the recruitment of tyrosine kinase SYK. Triggers activation of myeloid cells when associated with TYROBP.
  • 基因功能参考文献：
    1. SIRPB1 copy-number polymorphism was significantly associated with impulsive-disinhibited personality scores in a dose-dependent manner. PMID: 25039969
    2. SIRPbeta1 is a novel IFN-induced microglial receptor that supports clearance of neural debris and Abeta aggregates by stimulating phagocytosis. PMID: 19893026
    3. SIRP beta 1 is a disulfide-linked homodimer in leukocytes that regulates neutrophil transepithelial migration PMID: 16081415
    4. This protein has been found differentially expressed in the temporal lobe from patients with schizophrenia. PMID: 19034380
  • 亚细胞定位：
    Cell membrane; Single-pass type I membrane protein.
  • 组织特异性：
    Detected in monocytes and dendritic cells.
  • 数据库链接：

    HGNC: 15928

    OMIM: 603889

    UniGene: Hs.664861