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SLC25A14 Antibody

  • 货号：
    CSB-PA021480LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Immunofluorescent analysis of MCF-7 cells using CSB-PA021480LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
    • Immunohistochemistry of paraffin-embedded human testis tissue using CSB-PA021480LA01HU at dilution of 1:100
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) SLC25A14 Polyclonal antibody
  • Uniprot No.：
    O95258
  • 基因名：
    SLC25A14
  • 别名：
    SLC25A14; BMCP1; UCP5; UNQ791/PRO1682; Brain mitochondrial carrier protein 1; BMCP-1; Mitochondrial uncoupling protein 5; UCP 5; Solute carrier family 25 member 14
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human Brain mitochondrial carrier protein 1 protein (55-111AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，SLC25A14 Antibody (CSB-PA021480LA01HU)，的标记方式是Non-conjugated。对于SLC25A14 Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA021480LB01HU SLC25A14 Antibody, HRP conjugated ELISA
    FITC CSB-PA021480LC01HU SLC25A14 Antibody, FITC conjugated
    Biotin CSB-PA021480LD01HU SLC25A14 Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, IHC, IF
  • 推荐稀释比：
    Application Recommended Dilution
    IHC 1:20-1:200
    IF 1:50-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Participates in the mitochondrial proton leak measured in brain mitochondria.
  • 基因功能参考文献：
    1. Increased expression of cerebral UCP5 and UCP4 is observed in a model of high altitude hypoxia and mitochondrial oxidative phosphorylation deficiency. PMID: 23266757
    2. Neuronal UCP5 exhibits transmembrane chloride transport activity. PMID: 22524567
    3. observed significant associations between genetic variants in the SIRT6 and UCP5 genes and atherosclerotic plaque PMID: 22087257
    4. The enhanced level of UCP5 is associated to mitochondrial dysfunction in colonic cells. PMID: 19910678
    5. expressed in skeletal muscle as three different isoforms; expression level of UCP5SI positively correlated with resting metabolic rate and lipid oxidation rate during a euglycemic clamp with infusion of insulin at a physiologic concentration PMID: 12051969
    6. UCP5 might be physiologically important in the pathology of oxidative stress-induced neurodegeneration PMID: 16941493
    7. The brain may respond to neuroprotection through the increased expression of UCP5 under ischemic conditions. PMID: 18018477

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  • 亚细胞定位：
    Mitochondrion inner membrane; Multi-pass membrane protein.
  • 蛋白家族：
    Mitochondrial carrier (TC 2.A.29) family
  • 组织特异性：
    Mainly expressed in brain. Some expression in testis and pituitary.
  • 数据库链接：

    HGNC: 10984

    OMIM: 300242

    KEGG: hsa:9016

    STRING: 9606.ENSP00000218197

    UniGene: Hs.194686