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SLC25A2 Antibody

  • 货号：
    CSB-PA964037
  • 规格：
    ￥1100
  • 图片：
    • The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA964037(SLC25A2 Antibody) at dilution 1/20, on the right is treated with fusion protein. (Original magnification: ×200)
  • 其他：

产品详情

  • Uniprot No.：
    Q9BXI2
  • 基因名：
    SLC25A2
  • 别名：
    SLC25A2; ORNT2; Mitochondrial ornithine transporter 2; Solute carrier family 25 member 2
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Fusion protein of Human SLC25A2
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen affinity purification
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,IHC
  • 推荐稀释比：
    Application Recommended Dilution
    ELISA 1:2000-1:5000
    IHC 1:20-1:100
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Ornithine transport across inner mitochondrial membrane, from the cytoplasm to the matrix.
  • 基因功能参考文献：
    1. characterized mutations of the proposed substrate binding site in ORC1 and ORC2; demonstrated that the residue at position 179 in the 2 soforms is largely responsible for the difference in their substrate specificity;concluded that Arg-179 is a key residue in the opening of the carrier to the matrix side PMID: 22262851
    2. expression, reconstitution, functional characterization, and tissue distribution of two human isoforms ORC1 and ORC2 PMID: 12807890
    3. Here we identify a new intronless gene, ORNT2, located on chromosome 5. PMID: 12948741
  • 亚细胞定位：
    Mitochondrion inner membrane; Multi-pass membrane protein.
  • 蛋白家族：
    Mitochondrial carrier (TC 2.A.29) family
  • 组织特异性：
    Expressed in liver, kidney, pancreas and cultured fibroblasts.
  • 数据库链接：

    HGNC: 22921

    OMIM: 608157

    KEGG: hsa:83884

    STRING: 9606.ENSP00000239451

    UniGene: Hs.97647