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SLC25A3 Antibody

  • 货号：
    CSB-PA021499GA01HU
  • 规格：
    ￥3,900
  • 其他：

产品详情

  • Uniprot No.：
    Q00325
  • 基因名：
    SLC25A3
  • 别名：
    mitochondrial antibody; Mitochondrial phosphate carrier protein antibody; MPCP_HUMAN antibody; OK/SW cl.48 antibody; PHC antibody; Phosphate carrier protein antibody; Phosphate carrier protein mitochondrial antibody; Phosphate carrier protein mitochondrial precursor antibody; Phosphate transport protein antibody; PTP antibody; Slc25a3 antibody; Solute carrier family 25 member 3 antibody; Solute carrier family 25 mitochondrial carrier phosphate carrier member 3 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Human SLC25A3
  • 免疫原种属：
    Homo sapiens (Human)
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity Purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,IHC
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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靶点详情

  • 功能：
    Transport of phosphate groups from the cytosol to the mitochondrial matrix. Phosphate is cotransported with H(+). May play a role regulation of the mitochondrial permeability transition pore (mPTP).
  • 基因功能参考文献：
    1. these results indicate that PiC depletion may need to be profound (>85%) to substantially affect maximal oxphos and that pathogenesis associated with PiC depletion or loss of function may be independent of phosphate limitation when ATP requirements are not high. PMID: 27780865
    2. Compares and contrasts all the known human SLC25A* genes and includes functional information. PMID: 23266187
    3. An analysis of the promoter region of the human mitochondrial phosphate transporter, including its activation and inhibition domains, is reported. PMID: 15984930
    4. SLC25A3 protein deficiency is associated with lactic acidosis, hypertrophic cardiomyopathy, and muscular hypotonia PMID: 17273968
  • 相关疾病：
    Mitochondrial phosphate carrier deficiency (MPCD)
  • 亚细胞定位：
    Mitochondrion inner membrane; Multi-pass membrane protein.
  • 蛋白家族：
    Mitochondrial carrier (TC 2.A.29) family
  • 数据库链接：

    HGNC: 10989

    OMIM: 600370

    KEGG: hsa:5250

    STRING: 9606.ENSP00000228318

    UniGene: Hs.290404