SLC25A6 Antibody
-
货号:CSB-PA238544
-
规格:¥2024
-
图片:
-
其他:
产品详情
-
产品名称:Rabbit anti-Homo sapiens (Human) SLC25A6 Polyclonal antibody
-
Uniprot No.:P12236
-
基因名:
-
别名:SLC25A6; AAC3; ANT3; CDABP0051; ADP/ATP translocase 3; ADP,ATP carrier protein 3; ADP,ATP carrier protein, isoform T2; ANT 2; Adenine nucleotide translocator 3; ANT 3; Solute carrier family 25 member 6
-
宿主:Rabbit
-
反应种属:Human
-
免疫原:Synthesized peptide derived from internal of Human SLC25A6.
-
免疫原种属:Homo sapiens (Human)
-
克隆类型:Polyclonal
-
纯化方式:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
-
浓度:It differs from different batches. Please contact us to confirm it.
-
产品提供形式:Liquid
-
应用范围:ELISA,WB
-
推荐稀释比:
Application Recommended Dilution WB 1:500-1:3000 -
Protocols:
-
储存条件:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
-
货期:Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
相关产品
靶点详情
-
功能:ADP:ATP antiporter that mediates import of ADP into the mitochondrial matrix for ATP synthesis, and export of ATP out to fuel the cell. Cycles between the cytoplasmic-open state (c-state) and the matrix-open state (m-state): operates by the alternating access mechanism with a single substrate-binding site intermittently exposed to either the cytosolic (c-state) or matrix (m-state) side of the inner mitochondrial membrane. In addition to its ADP:ATP antiporter activity, also involved in mitochondrial uncoupling and mitochondrial permeability transition pore (mPTP) activity. Plays a...显示更多
-
基因功能参考文献:
- Human ANT3 expression is directly downregulated by overexpression of hcmv-miR-UL36-5p. PMID: 26212361
- The dynamics of the molecular interactions between the C-terminal region of PB1-F2 protein and VDAC1 and ANT3 were expounded by employing an in silico approach. PMID: 19669810
- Of three ANT isoforms expressed in yeast, ANC3 is the most efficient to restore yeast growth on a nonfermentable carbon source of a yeast mutant strain lacking its three endogenous ANC. PMID: 12450408
- Results demonstrate that induction of adenine nucleotide translocase 3 by interleukin-4 and interferon-gamma proceeds via pathways involving STAT6 and STAT1, respectively. PMID: 14746803
- ANT3 overexpression induces apoptosis in cultured cells. PMID: 15063741
- ANT3 has a potential role in T-helper cell survival and immune cell homeostasis. PMID: 16930576
- involvement of ANT in cell death is cell type- and stimulus-dependent PMID: 17855512
- These data suggest that the down-regulation of ANT3 levels upon stimulation with CPT may be involved in the molecular mechanism underlying acquired resistance to camptothecin. PMID: 19111545
收起更多
-
亚细胞定位:Mitochondrion inner membrane; Multi-pass membrane protein. Membrane; Multi-pass membrane protein.
-
蛋白家族:Mitochondrial carrier (TC 2.A.29) family
-
组织特异性:Expressed in erythrocytes (at protein level).
-
数据库链接:
HGNC: 10992
OMIM: 300151
KEGG: hsa:293
STRING: 9606.ENSP00000370808
UniGene: Hs.350927