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SLC30A7 Antibody

  • 货号：
    CSB-PA836732LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Western Blot
      Positive WB detected in: Mouse heart tissue, Mouse skeletal muscle tissue
      All lanes: SLC30A7 antibody at 3μg/ml
      Secondary
      Goat polyclonal to rabbit IgG at 1/50000 dilution
      Predicted band size: 42 kDa
      Observed band size: 42 kDa
    • Immunohistochemistry of paraffin-embedded human placenta tissue using CSB-PA836732LA01HU at dilution of 1:100
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) SLC30A7 Polyclonal antibody
  • Uniprot No.：
    Q8NEW0
  • 基因名：
  • 别名：
    SLC30A7; ZNT7; ZNTL2; Zinc transporter 7; ZnT-7; Solute carrier family 30 member 7; Znt-like transporter 2
  • 宿主：
    Rabbit
  • 反应种属：
    Human, Mouse
  • 免疫原：
    Recombinant Human Zinc transporter 7 protein (162-236AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，SLC30A7 Antibody (CSB-PA836732LA01HU)，的标记方式是Non-conjugated。对于SLC30A7 Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA836732LB01HU SLC30A7 Antibody, HRP conjugated ELISA
    FITC CSB-PA836732LC01HU SLC30A7 Antibody, FITC conjugated
    Biotin CSB-PA836732LD01HU SLC30A7 Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, WB, IHC
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:1000-1:5000
    IHC 1:20-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Seems to facilitate zinc transport from the cytoplasm into the Golgi apparatus. Partly regulates cellular zinc homeostasis. Required with ZNT5 for the activation of zinc-requiring enzymes, alkaline phosphatases (ALPs). Transports zinc into the lumens of the Golgi apparatus and the vesicular compartments where ALPs locate, thus, converting apoALPs to holoALPs. Required with ZNT5 and ZNT6 for the activation of TNAP.
  • 基因功能参考文献：
    1. We observed Bonferroni-corrected statistically significant interactions between albuminuria, urine cadmium levels and polymorphisms in gene SLC30A7 and RAC1. PMID: 28558300
    2. Overexpression of ZnT7 is accompanied by activation of PI3K/Akt pathway and inhibiting HG-induced apoptosis. PMID: 23275032
    3. Intracellular transporters such as ZnT7, influence the transcellular movement of zinc across the enterocyte PMID: 21462106
    4. hZnT-7 is up-regulated in response to cellular zinc depletion in Raji & THP-1 cells. PMID: 17971500
    5. Data show that ZNT7 is extensively present in the Abeta-positive plaques in the cortex of human AD brains. PMID: 18639746

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  • 亚细胞定位：
    Golgi apparatus, trans-Golgi network membrane; Multi-pass membrane protein.
  • 蛋白家族：
    Cation diffusion facilitator (CDF) transporter (TC 2.A.4) family, SLC30A subfamily
  • 数据库链接：

    HGNC: 19306

    OMIM: 611149

    KEGG: hsa:148867

    STRING: 9606.ENSP00000350278

    UniGene: Hs.533903