Your Good Partner in Biology Research

  1. Home
  2. 抗体
  3. 多克隆抗体
  4. SLIT1 Antibody

SLIT1 Antibody

  • 货号：
    CSB-PA258249
  • 规格：
    ￥1100
  • 图片：
    • The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA258249(SLIT1 Antibody) at dilution 1/35, on the right is treated with synthetic peptide. (Original magnification: ×200)
    • The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using CSB-PA258249(SLIT1 Antibody) at dilution 1/35, on the right is treated with synthetic peptide. (Original magnification: ×200)
  • 其他：

产品详情

  • Uniprot No.：
    O75093
  • 基因名：
    SLIT1
  • 别名：
    KIAA0813 antibody; MEGF 4 antibody; MEGF4 antibody; MGC164811 antibody; Multiple EGF-like domains protein 4 antibody; Multiple epidermal growth factor like domains 4 antibody; Multiple epidermal growth factor-like domains protein 4 antibody; OTTHUMP00000059392 antibody; SLIL 1 antibody; SLIL1 antibody; Slit 1 antibody; SLIT 3 antibody; Slit homolog 1 antibody; Slit homolog 1 protein antibody; Slit-1 antibody; Slit1 antibody; SLIT1_HUMAN antibody; SLIT3 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse,Rat
  • 免疫原：
    Synthetic peptide of Human SLIT1
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen affinity purification
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,IHC
  • 推荐稀释比：
    Application Recommended Dilution
    ELISA 1:1000-1:2000
    IHC 1:25-1:100
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Thought to act as molecular guidance cue in cellular migration, and function appears to be mediated by interaction with roundabout homolog receptors. During neural development involved in axonal navigation at the ventral midline of the neural tube and projection of axons to different regions. SLIT1 and SLIT2 together seem to be essential for midline guidance in the forebrain by acting as repulsive signal preventing inappropriate midline crossing by axons projecting from the olfactory bulb.
  • 基因功能参考文献：
    1. Analysis of alternative splicing and conserved domains in human and mouse slit genes PMID: 12141424
    2. evidence showing that Slit1 and Slit2 proteins are selective inhibitors and repellents for dorsally projecting, but not for ventrally projecting, cranial motor axons PMID: 16162649
    3. In fetal and embryonic stem cell cultures Slit-1 inhibited neurite outgrowth. PMID: 16840550
  • 亚细胞定位：
    Secreted.
  • 组织特异性：
    Predominantly expressed in adult forebrain. Expressed in fetal brain, lung and kidney.
  • 数据库链接：

    HGNC: 11085

    OMIM: 603742

    KEGG: hsa:6585

    STRING: 9606.ENSP00000266058

    UniGene: Hs.632082