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SLITRK6 Antibody

  • 货号：
    CSB-PA867155LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Immunohistochemistry of paraffin-embedded human thyroid tissue using CSB-PA867155LA01HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human lung tissue using CSB-PA867155LA01HU at dilution of 1:100
    • Immunofluorescent analysis of HepG2 cells using CSB-PA867155LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) SLITRK6 Polyclonal antibody
  • Uniprot No.：
    Q9H5Y7
  • 基因名：
  • 别名：
    4832410J21Rik antibody; DFNMYP antibody; MGC119595 antibody; MGC119596 antibody; MGC119597 antibody; OTTHUMP00000066012 antibody; SLIK6_HUMAN antibody; SLIT and NTRK like family member 6 antibody; SLIT and NTRK like protein 6 antibody; SLIT and NTRK-like protein 6 antibody; Slit and trk like 6 antibody; Slit and trk like gene 6 antibody; SLITRK 6 antibody; Slitrk6 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human SLIT and NTRK-like protein 6 protein (621-821AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，SLITRK6 Antibody (CSB-PA867155LA01HU)，的标记方式是Non-conjugated。对于SLITRK6 Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA867155LB01HU SLITRK6 Antibody, HRP conjugated ELISA
    FITC CSB-PA867155LC01HU SLITRK6 Antibody, FITC conjugated
    Biotin CSB-PA867155LD01HU SLITRK6 Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, IHC, IF
  • 推荐稀释比：
    Application Recommended Dilution
    IHC 1:20-1:200
    IF 1:50-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Regulator of neurite outgrowth required for normal hearing and vision.
  • 基因功能参考文献：
    1. Analysis of two exons of SLITRK6 gene in a Moroccan family identify a novel single deleterious mutation c.696delG, p.Trp232Cysfs*10 at homozygous state in the exon 2 of the SLITRK6, a gene reported to cause deafness and myopia in various populations. PMID: 29551497
    2. Human cytomegalovirus downregulates SLITRK6 expression through IE2. PMID: 27530937
    3. SLITRK6 gene nonsense mutation is associated with progressive auditory neuropathy in humans. PMID: 23946138
    4. SLITRK6 plays a crucial role in the development of normal hearing as well as vision in humans and in mice and that its disruption leads to a syndrome characterized by severe myopia and deafness. PMID: 23543054
  • 相关疾病：
    Deafness and myopia (DFNMYP)
  • 亚细胞定位：
    Cell membrane; Single-pass type I membrane protein.
  • 蛋白家族：
    SLITRK family
  • 组织特异性：
    In adult brain, highly expressed in putamen with no expression in cerebral cortex. Expressed in adult and fetal lung and fetal liver. Also expressed at high levels in some brain tumors including medulloblastomas and primitive neuroectodermal tumors.
  • 数据库链接：

    HGNC: 23503

    OMIM: 221200

    KEGG: hsa:84189

    STRING: 9606.ENSP00000383143

    UniGene: Hs.525105