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SMAP1 Antibody

  • 货号:
    CSB-PA811625LA01HU
  • 规格:
    ¥440
  • 促销:
    小规格抗体限时一口价
  • 图片:
    • Immunohistochemistry of paraffin-embedded human appendix tissue using CSB-PA811625LA01HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human liver tissue using CSB-PA811625LA01HU at dilution of 1:100
  • 其他:

产品详情

  • 产品名称:
    Rabbit anti-Homo sapiens (Human) SMAP1 Polyclonal antibody
  • Uniprot No.:
    Q8IYB5
  • 基因名:
  • 别名:
    SMAP1 antibody; Stromal membrane-associated protein 1 antibody
  • 宿主:
    Rabbit
  • 反应种属:
    Human
  • 免疫原:
    Recombinant Human Stromal membrane-associated protein 1 protein (1-280AA)
  • 免疫原种属:
    Homo sapiens (Human)
  • 标记方式:
    Non-conjugated

    本页面中的产品,SMAP1 Antibody (CSB-PA811625LA01HU),的标记方式是Non-conjugated。对于SMAP1 Antibody,我们还提供其他标记。见下表:

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA811625LB01HU SMAP1 Antibody, HRP conjugated ELISA
    FITC CSB-PA811625LC01HU SMAP1 Antibody, FITC conjugated
    Biotin CSB-PA811625LD01HU SMAP1 Antibody, Biotin conjugated ELISA
  • 克隆类型:
    Polyclonal
  • 抗体亚型:
    IgG
  • 纯化方式:
    >95%, Protein G purified
  • 浓度:
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式:
    Liquid
  • 应用范围:
    ELISA, IHC
  • 推荐稀释比:
    Application Recommended Dilution
    IHC 1:20-1:200
  • Protocols:
  • 储存条件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能:
    GTPase activating protein that acts on ARF6. Plays a role in clathrin-dependent endocytosis. May play a role in erythropoiesis.
  • 基因功能参考文献:
    1. The study identified a region on chromosome 6 comprising the genes SMAP1, B3GAT2, and RIMS1 as novel susceptibility locus for pediatric venous thromboembolism. PMID: 28011674
    2. Results also demonstrated a physical association between SMAP1 and SMAP2, which might serve as a basis for a functional interaction, and identified the intramolecular domains responsible for this association PMID: 25281535
    3. SMAP1 loss-of-function mutations in microsatellite instability colorectal cancer may contribute to the emerging oncogenic pathway involving abnormal Arf6 regulation. PMID: 23752192
    4. SMAP1 may be an ADP-ribosylation factor 6 (Arf6)GAP that specifically regulates one of the multiple functions of Arf6, namely, clathrin-dependent endocytosis PMID: 15659652
  • 亚细胞定位:
    Cell membrane; Peripheral membrane protein; Cytoplasmic side.
  • 组织特异性:
    Detected in bone marrow, adrenal gland, trachea, lymph node, spinal cord, peripheral blood leukocytes, thyroid and stomach.
  • 数据库链接:

    HGNC: 19651

    OMIM: 611372

    KEGG: hsa:60682

    STRING: 9606.ENSP00000359484

    UniGene: Hs.485717