SMARCC2 Antibody
产品详情
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产品名称:Rabbit anti-Homo sapiens (Human) SMARCC2 Polyclonal antibody
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Uniprot No.:Q8TAQ2
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基因名:SMARCC2
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别名:SWI/SNF complex subunit SMARCC2 (BRG1-associated factor 170) (BAF170) (SWI/SNF complex 170 kDa subunit) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 2), SMARCC2, BAF170
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宿主:Rabbit
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反应种属:Human
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免疫原:Recombinant Human SWI/SNF complex subunit SMARCC2 protein (300-647aa)
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免疫原种属:Homo sapiens (Human)
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标记方式:Non-conjugated
本页面中的产品,SMARCC2 Antibody (CSB-PA851527LA11HU),的标记方式是Non-conjugated。对于SMARCC2 Antibody,我们还提供其他标记。见下表:
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克隆类型:Polyclonal
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抗体亚型:IgG
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纯化方式:>95%, Protein G purified
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浓度:It differs from different batches. Please contact us to confirm it.
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保存缓冲液:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 -
产品提供形式:Liquid
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应用范围:ELISA, IHC, IF
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推荐稀释比:
Application Recommended Dilution IHC 1:100-1:500 IF 1:100-1:500 -
Protocols:
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储存条件:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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货期:Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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靶点详情
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功能:Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Component of SWI/SNF chromatin remodeling complexes that carry out key enzymatic activities, changing chromatin structure by altering DNA-histone contacts within a nucleosome in an ATP-dependent manner. Can stimulate the ATPase activity of the catalytic subunit of these complexes. May be required for CoREST dependent repression of neuronal specific gene promoters in non-neuronal cells. Belongs to the neural progenitors-specific chromatin remodeling...显示更多
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基因功能参考文献:
- BAF170 is important for neurogenesis in embryonic olfactory epithelium. PMID: 27611684
- Identification of frameshift mutations in the SMARCC2 gene in gastric and colorectal cancers with microsatellite instability. PMID: 23030715
- study finds Baf53 and Baf170 are highly regulated in HIV-1-infected cells PMID: 21699904
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亚细胞定位:Nucleus.
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蛋白家族:SMARCC family
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组织特异性:Ubiquitously expressed.
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数据库链接:
HGNC: 11105
OMIM: 601734
KEGG: hsa:6601
STRING: 9606.ENSP00000267064
UniGene: Hs.236030