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SNTB1 Antibody

  • 货号：
    CSB-PA621699LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Immunofluorescence staining of HepG2 cells with CSB-PA621699LA01HU at 1:66, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) SNTB1 Polyclonal antibody
  • Uniprot No.：
    Q13884
  • 基因名：
    SNTB1
  • 别名：
    59 DAP antibody; 59 kDa dystrophin associated protein A1 basic component 1 antibody; 59 kDa dystrophin-associated protein A1 basic component 1 antibody; A1B antibody; Beta 1 syntrophin antibody; Beta-1-syntrophin antibody; BSYN2 antibody; DAPA1B antibody; Dystrophin associated protein A1 59kDa basic component 1 antibody; FLJ22442 antibody; MGC111389 antibody; SNT2 antibody; SNT2B1 antibody; SNTB 1 antibody; Sntb1 antibody; SNTB1_HUMAN antibody; Syntrophin 2 antibody; Syntrophin beta 1 antibody; Syntrophin beta 1 (dystrophin associated protein A1 59kDa basic component 1) antibody; Syntrophin-2 antibody; Tax interaction protein 43 antibody; TIP 43 antibody; TIP-43 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human Beta-1-syntrophin protein (51-111AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，SNTB1 Antibody (CSB-PA621699LA01HU)，的标记方式是Non-conjugated。对于SNTB1 Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA621699LB01HU SNTB1 Antibody, HRP conjugated ELISA
    FITC CSB-PA621699LC01HU SNTB1 Antibody, FITC conjugated
    Biotin CSB-PA621699LD01HU SNTB1 Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, IF
  • 推荐稀释比：
    Application Recommended Dilution
    IF 1:50-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Adapter protein that binds to and probably organizes the subcellular localization of a variety of membrane proteins. May link various receptors to the actin cytoskeleton and the dystrophin glycoprotein complex.
  • 基因功能参考文献：
    1. Our study confirms that the two susceptibility loci ZFHX1B and SNTB1 are associated with moderate to high myopia in a Han Chinese population, as well as in a European population, when both SNPs are combined. PMID: 28848321
    2. SNPs within the SNTB1 gene are associated with increased risk of oral cancer. PMID: 28595731
    3. SNTB1 and MCPH1 are located on chromosome 8, which may be involved in neuroticism, avoidant personality and depression. PMID: 24975899
    4. beta1-syntrophin acts through a class-I PDZ interaction with the C terminus of ABCA1 to regulate the cellular distribution and activity of the transporter PMID: 16192269
  • 亚细胞定位：
    Cell membrane, sarcolemma; Peripheral membrane protein; Cytoplasmic side. Cell junction. Cytoplasm, cytoskeleton.
  • 蛋白家族：
    Syntrophin family
  • 组织特异性：
    Ubiquitous.
  • 数据库链接：

    HGNC: 11168

    OMIM: 600026

    KEGG: hsa:6641

    STRING: 9606.ENSP00000378965

    UniGene: Hs.46701