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SOX13 Antibody

  • 货号：
    CSB-PA699917
  • 规格：
    ￥1100
  • 图片：
    • The image on the left is immunohistochemistry of paraffin-embedded Human tonsil tissue using CSB-PA699917(SOX13 Antibody) at dilution 1/50, on the right is treated with synthetic peptide. (Original magnification: ×200)
    • The image on the left is immunohistochemistry of paraffin-embedded Human lung cancer tissue using CSB-PA699917(SOX13 Antibody) at dilution 1/50, on the right is treated with synthetic peptide. (Original magnification: ×200)
    • Gel: 10%SDS-PAGE, Lysate: 40 μg, Lane: Mouse liver tissue, Primary antibody: CSB-PA699917(SOX13 Antibody) at dilution 1/800, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 minute
  • 其他：

产品详情

  • Uniprot No.：
    Q9UN79
  • 基因名：
    SOX13
  • 别名：
    ICA 12 antibody; ICA12 antibody; Islet cell antibody 12 antibody; Islet cell antigen 12 antibody; MGC117216 antibody; SOX 13 antibody; SOX 13 protein antibody; sox13 antibody; SOX13 protein antibody; SOX13_HUMAN antibody; SRY (Sex determining region Y)-box 13 antibody; SRY box 13 antibody; SRY box containing gene 13 antibody; SRY related HMG box gene 13 antibody; SRY sex determining region Y box 13 antibody; Transcription factor SOX 13 antibody; Transcription factor Sox-13 antibody; Type 1 diabetes autoantigen antibody; Type 1 diabetes autoantigen ICA 12 antibody; Type 1 diabetes autoantigen ICA12 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse
  • 免疫原：
    Synthetic peptide of Human SOX13
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen affinity purification
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,WB,IHC
  • 推荐稀释比：
    Application Recommended Dilution
    ELISA 1:2000-1:5000
    WB 1:500-1:2000
    IHC 1:50-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Transcription factor that binds to DNA at the consensus sequence 5'-AACAAT-3'. Binds to the proximal promoter region of the myelin protein MPZ gene, and may thereby be involved in the differentiation of oligodendroglia in the developing spinal tube. Binds to the gene promoter of MBP and acts as a transcriptional repressor. Binds to and modifies the activity of TCF7/TCF1, thereby inhibiting transcription and modulates normal gamma-delta T-cell development and differentiation of IL17A expressing gamma-delta T-cells. Regulates expression of BLK in the differentiation of IL17A expressing gamma-delta T-cells. Promotes brown adipocyte differentiation. Inhibitor of WNT signaling.
  • 基因功能参考文献：
    1. the interaction between Hhex and SOX13 may contribute to control Wnt/TCF1 signaling in the early embryo. PMID: 20028982
  • 亚细胞定位：
    Nucleus. Cytoplasm.
  • 组织特异性：
    Expressed in exocrine cells and islets of Langerhans in the pancreas (at protein level). Expressed in the pancreas, placenta, kidney, brain, heart, lung, and liver. Expressed in adipose tissue, cervix, colon, esophagus, ovary, prostate, small intestine, s
  • 数据库链接：

    HGNC: 11192

    OMIM: 604748

    KEGG: hsa:9580

    STRING: 9606.ENSP00000356172

    UniGene: Hs.201671