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SPIC Antibody

  • 货号：
    CSB-PA004137
  • 规格：
    ￥880
  • 图片：
    • Western Blot analysis of HeLa cells using Spi-C Polyclonal Antibody
  • 其他：

产品详情

  • Uniprot No.：
    Q8N5J4
  • 基因名：
    SPIC
  • 别名：
    AU019198 antibody; C76795 antibody; MGC40611 antibody; MGC80555 antibody; Prf antibody; Pu.1 related factor antibody; Spi C antibody; Spi C transcription factor antibody; Spi-C transcription factor (Spi-1/PU.1 related) antibody; spiC antibody; SPIC_HUMAN antibody; Transcription factor Spi-C antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Synthesized peptide derived from the Internal region of Human Spi-C.
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 抗体亚型：
    IgG
  • 纯化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 产品提供形式：
    Liquid
  • 应用范围：
    WB, IF, ELISA
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:2000
    IF 1:200-1:1000
    ELISA 1:10000
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Controls the development of red pulp macrophages required for red blood cells recycling and iron homeostasis. Transcription factor that binds to the PU-box, a purine-rich DNA sequence (5'-GAGGA[AT]-3') that can act as a lymphoid-specific enhancer. Regulates VCAM1 gene expression.
  • 基因功能参考文献：
    1. A protein interaction between SPI-C and STAT6 is the basis for a novel mechanism for regulation of IL4 induced gene expression. PMID: 16647686
  • 亚细胞定位：
    Nucleus.
  • 蛋白家族：
    ETS family
  • 组织特异性：
    Preferentially detected in fetal and adult spleen, lymph nodes and at lower levels in bone marrow and fetal liver.
  • 数据库链接：

    HGNC: 29549

    OMIM: 612568

    KEGG: hsa:121599

    STRING: 9606.ENSP00000299272

    UniGene: Hs.577097