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SPIRE2 Antibody

  • 货号：
    CSB-PA855490LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Immunohistochemistry of paraffin-embedded human kidney tissue using CSB-PA855490LA01HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human gastric cancer using CSB-PA855490LA01HU at dilution of 1:100
    • Immunofluorescent analysis of MCF-7 cells using CSB-PA855490LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) SPIRE2 Polyclonal antibody
  • Uniprot No.：
    Q8WWL2
  • 基因名：
    SPIRE2
  • 别名：
    MGC117166 antibody; Protein spire homolog 2 antibody; Spir-2 antibody; SPIR2_HUMAN antibody; Spire homolog 2 (Drosophila) antibody; SPIRE2 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human Protein spire homolog 2 protein (79-388AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，SPIRE2 Antibody (CSB-PA855490LA01HU)，的标记方式是Non-conjugated。对于SPIRE2 Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA855490LB01HU SPIRE2 Antibody, HRP conjugated ELISA
    FITC CSB-PA855490LC01HU SPIRE2 Antibody, FITC conjugated
    Biotin CSB-PA855490LD01HU SPIRE2 Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, IHC, IF
  • 推荐稀释比：
    Application Recommended Dilution
    IHC 1:20-1:200
    IF 1:50-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Acts as an actin nucleation factor, remains associated with the slow-growing pointed end of the new filament. Involved in intracellular vesicle transport along actin fibers, providing a novel link between actin cytoskeleton dynamics and intracellular transport. Required for asymmetric spindle positioning and asymmetric cell division during meiosis. Required for normal formation of the cleavage furrow and for polar body extrusion during female germ cell meiosis. Also acts in the nucleus: together with SPIRE1 and SPIRE2, promotes assembly of nuclear actin filaments in response to DNA damage in order to facilitate movement of chromatin and repair factors after DNA damage.
  • 基因功能参考文献：
    1. influences intracellular replication of Salmonella typhimurium PMID: 27627128
  • 亚细胞定位：
    Cytoplasm, cytoskeleton. Cytoplasm, cytosol. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side.
  • 蛋白家族：
    Spire family
  • 数据库链接：

    HGNC: 30623

    OMIM: 609217

    KEGG: hsa:84501

    STRING: 9606.ENSP00000367494

    UniGene: Hs.461786