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SPRY3 Antibody

  • 货号：
    CSB-PA022623GA01HU
  • 规格：
    ￥3,900
  • 其他：

产品详情

  • Uniprot No.：
    O43610
  • 基因名：
    SPRY3
  • 别名：
    SPRY3 antibody; Protein sprouty homolog 3 antibody; Spry-3 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse,Rat
  • 免疫原：
    Human SPRY3
  • 免疫原种属：
    Homo sapiens (Human)
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,WB
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Inhibits neurite branching, arbor length and neurite complexity. Inhibits EGF-mediated p42/44 ERK signaling. Negatively regulates the MAPK cascade, resulting in a reduction of extracellular matrix protein accumulation. May function as an antagonist of fibroblast growth factor (FGF) pathways and may negatively modulate respiratory organogenesis.
  • 基因功能参考文献：
    1. SPRY3 is a candidate susceptibility locus for autism and related or over-lapping disorders such as ataxia. PMID: 26089202
    2. Spry 1, 2 and 3 expression was observed in placental tissue from all three trimesters PMID: 15950061
    3. the Sprouty/Caveolin-1 interaction modulates signaling in a growth factor- and Sprouty isoform-specific manner PMID: 16877379
  • 亚细胞定位：
    Cytoplasm.
  • 蛋白家族：
    Sprouty family
  • 组织特异性：
    Widely expressed; particularly in the fetal tissues. Expressed in the brain with expression the highest in Purkinje cells in the cerebellum (at protein level). Expressed in the myocardium of the heart.
  • 数据库链接：

    HGNC: 11271

    OMIM: 300531

    KEGG: hsa:10251

    STRING: 9606.ENSP00000302978

    UniGene: Hs.381912