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SPZ1 Antibody

  • 货号：
    CSB-PA070038
  • 规格：
    ￥880
  • 其他：

产品详情

  • Uniprot No.：
    Q9BXG8
  • 基因名：
    SPZ1
  • 别名：
    SPZ1 antibody; TSP1 antibody; Spermatogenic leucine zipper protein 1 antibody; Testis-specific protein 1 antibody; Testis-specific protein NYD-TSP1 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Synthesized peptide derived from the N-terminal region of Human SPZ1.
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 抗体亚型：
    IgG
  • 纯化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 产品提供形式：
    Liquid
  • 应用范围：
    IHC, IF, ELISA
  • 推荐稀释比：
    Application Recommended Dilution
    IHC 1:100-1:300
    IF 1:200-1:1000
    ELISA 1:20000
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Transcription factor that binds to the DNA sequence 5'-CANNTG-3'(E box) and the G-box motif. May play an important role in the regulation of cell proliferation and differentiation during spermatogenesis.
  • 基因功能参考文献：
    1. SPZ1 promotes epithelial-mesenchymal transition (EMT) by trans-activating the gene of TWIST1. A clinical analysis showed a marker association of SPZ1 and TWIST1 with induction of tumorigenesis in HCC patients. PMID: 28368406
    2. highly expressed in adult testis; may play an important role in spermatogenesis in the humans PMID: 12778315
  • 亚细胞定位：
    Cytoplasm. Nucleus.
  • 组织特异性：
    Specifically and strongly expressed in the testis. Expressed in several tumor cell lines.
  • 数据库链接：

    HGNC: 30721

    KEGG: hsa:84654

    STRING: 9606.ENSP00000369611

    UniGene: Hs.519403