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ST6GALNAC1 Antibody

  • 货号：
    CSB-PA022761GA01HU
  • 规格：
    ￥3,900
  • 其他：

产品详情

  • Uniprot No.：
    Q9NSC7
  • 基因名：
    ST6GALNAC1
  • 别名：
    6-sialyltransferase 1 antibody; 6-sialyltransferase I antibody; Alpha N acetylgalactosaminide alpha 2 6 sialyltransferase 1 antibody; Alpha N acetylgalactosaminide alpha 2 6 sialyltransferase antibody; Alpha-N-acetylgalactosaminide alpha-2 antibody; GalNAc alpha 2 6 sialyltransferase I antibody; GalNAc alpha-2 antibody; HSY11339 antibody; SIA7A_HUMAN antibody; Sialyltransferase 7A antibody; SIAT7-A antibody; SIAT7A antibody; ST6 (alpha N acetyl neuraminyl 2 3 beta galactosyl 1 3) N acetylgalactosaminide alpha 2 6 sialyltransferase 1 antibody; ST6GalNAc I antibody; ST6GALNAC1 antibody; ST6GalNAcI antibody; STYI antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse,Rat
  • 免疫原：
    Human ST6GALNAC1
  • 免疫原种属：
    Homo sapiens (Human)
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,WB
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 基因功能参考文献：
    1. Our results indicated that ST6GALNAC1 was downregulated in sporadic esophageal squamous cell carcinoma via hyper-methylation and loss of heterozygosity , and it may be a candidate responsible gene for esophageal squamous cell carcinoma PMID: 28035351
    2. ST6GalNAc I regulates the gene expression of IGF-1 through STAT5b activation and plays role in gastric cancer invasion and metastasis. PMID: 25532910
    3. upregulated Siat7A expression, which was paralleled by the increased Klf4 in the ischemic myocardium, contributed to cardiomyocyte apoptosis following myocardial infarction PMID: 25860962
    4. Using qRT-PCR, sialyl-Tn expression was found to be associated with an increase in alpha2,6-sialyltransferase gene (ST6GALNAC1) and a decrease in core 1 synthase gene (C1GALT1) in LS174T cells. PMID: 24840470
    5. It was confirmed that MUC1 carries sialyl Tn also in human advanced gastric cancer tissues PMID: 22228572
    6. The stable transfection of MDA-MB-231 with an expression vector encoding ST6GalNAc I induces the expression of STn antigen at the cell surface. PMID: 12820722
    7. ST6GalNAc-I sialyltransferase localizes throughout the Golgi and has a role in synthesis of the tumor-associated sialyl-Tn O-glycan in human breast cancer PMID: 16319059
    8. Expression of ppGalNAc-T6 is significantly higher in breast cancer compared to 'normal'/benign breast tissue samples. ST6GalNAc-I expression in breast cancer is associated with better prognosis. PMID: 19287074

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  • 亚细胞定位：
    Golgi apparatus membrane; Single-pass type II membrane protein.
  • 蛋白家族：
    Glycosyltransferase 29 family
  • 数据库链接：

    HGNC: 23614

    OMIM: 610138

    KEGG: hsa:55808

    STRING: 9606.ENSP00000156626

    UniGene: Hs.105352