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STK38L Antibody

  • 货号：
    CSB-PA008304
  • 规格：
    ￥880
  • 图片：
    • Western Blot analysis of mouse cells using NDR2 Polyclonal Antibody
  • 其他：

产品详情

  • Uniprot No.：
    Q9Y2H1
  • 基因名：
    STK38L
  • 别名：
    KIAA0965 antibody; NDR2 antibody; NDR2 protein kinase antibody; nuclear Dbf2 related 2 antibody; Nuclear Dbf2 related kinase 2 antibody; Nuclear Dbf2-related kinase 2 antibody; Serine/threonine protein kinase 38 like antibody; Serine/threonine-protein kinase 38-like antibody; ST38L_HUMAN antibody; Stk38l antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse,Rat
  • 免疫原：
    Synthesized peptide derived from the C-terminal region of Human NDR2.
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 抗体亚型：
    IgG
  • 纯化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 产品提供形式：
    Liquid
  • 应用范围：
    WB, IHC, ELISA
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:2000
    IHC 1:100-1:300
    IHC 1:200-1:1000
    ELISA 1:5000
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Involved in the regulation of structural processes in differentiating and mature neuronal cells.
  • 基因功能参考文献：
    1. It was found that STK38L*I/D genotype had positive association with longevity in the ethnically homogeneous group of Tatars from the Republic of Bashkortostan, Russia. PMID: 28556638
    2. NDR2-mediated Rabin8 phosphorylation is crucial for ciliogenesis by triggering the switch in binding specificity of Rabin8 from PS to Sec15. PMID: 23435566
    3. Activation of NDR2 is a multistep process involving phosphorylation of the hydrophobic motif site Thr444/2 by MST3, autophosphorylation of Ser281/2, and binding of MOB1A. PMID: 16314523
    4. NDR2 is an upstream kinase of ARK5 that plays an essential role in tumor progression through ARK5 PMID: 16488889
  • 亚细胞定位：
    Cytoplasm. Cytoplasm, cytoskeleton. Membrane. Note=Associated with the actin cytoskeleton. Co-localizes with STK24/MST3 in the membrane.
  • 蛋白家族：
    Protein kinase superfamily, AGC Ser/Thr protein kinase family
  • 组织特异性：
    Ubiquitously expressed with highest levels observed in the thymus.
  • 数据库链接：

    HGNC: 17848

    OMIM: 615836

    KEGG: hsa:23012

    STRING: 9606.ENSP00000373684

    UniGene: Hs.184523