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SULT4A1 Antibody

  • 货号：
    CSB-PA022944GA01HU
  • 规格：
    ￥3,900
  • 其他：

产品详情

  • Uniprot No.：
    Q9BR01
  • 基因名：
    SULT4A1
  • 别名：
    BR STL 1 antibody; Brain sulfotransferase like protein antibody; Brain sulfotransferase-like protein antibody; Brain sulphotransferase like antibody; BRSTL1 antibody; DJ388M5.3 antibody; hBR STL 1 antibody; hBR STL antibody; hBR-STL antibody; hBR-STL-1 antibody; MGC40032 antibody; Nervous system cytosolic sulfotransferase antibody; Nervous system sulfotransferase antibody; NST antibody; OTTHUMP00000028875 antibody; ST4A1 antibody; ST4A1_HUMAN antibody; Sulfotransferase 4A1 antibody; Sulfotransferase family 4A member 1 antibody; Sulfotransferase related protein antibody; SULT4A1 antibody; SULTX3 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse,Rat
  • 免疫原：
    Human SULT4A1
  • 免疫原种属：
    Homo sapiens (Human)
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity Purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,WB
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Atypical sulfotransferase family member with very low affinity for 3'-phospho-5'-adenylyl sulfate (PAPS) and very low catalytic activity towards L-triiodothyronine, thyroxine, estrone, p-nitrophenol, 2-naphthylamine, and 2-beta-naphthol. May have a role in the metabolism of drugs and neurotransmitters in the CNS.
  • 基因功能参考文献：
    1. These results show that SULT4A1 is widely expressed in human tissues, but mostly as a splice variant that produces a rapidly degraded protein. Dimerization protects the protein from degradation. PMID: 24988429
    2. Across three psychiatric disorders (n=2815 patients), we observed no consistent association between SULT4A1-1 status and atypical antipsychotic effect PMID: 25340730
    3. This study provides a second replication of superior olanzapine response in SULT4A1-1-positive subjects compared with SULT4A1-1-negative subjects. PMID: 24956247
    4. determination of SULT4A1-1 haplotype status might be useful for identifying patients who show an enhanced response to long-term olanzapine treatment. PMID: 21521020
    5. the first immunohistochemical localization of SULT4A1 in human brain PMID: 14623933
    6. Candidate gene for schizophrenia susceptibility. PMID: 16152568
    7. These results provide the first evidence of how genetic variation in Sult4A1 may be related to clinical symptoms and cognitive function in schizophrenia PMID: 18823757
    8. The lack of polymorphisms in the coding region of the SULT4A1 gene is highly unusual and, along with its high conservation between species, suggests that SULT4A1 may have an important function in vivo. PMID: 19125109
    9. Cytosolic SULT4A1 interacts with PIN1. PMID: 19439498

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  • 亚细胞定位：
    Cytoplasm.
  • 蛋白家族：
    Sulfotransferase 1 family
  • 组织特异性：
    Highly expressed in the cerebral cortex and frontal lobe, slightly less in the cerebellum, occipital and temporal lobes, relatively low in the medulla and putamen, and lowest in the spinal cord. No expression detected in the pancreas. Highly expressed in
  • 数据库链接：

    HGNC: 14903

    OMIM: 608359

    KEGG: hsa:25830

    STRING: 9606.ENSP00000332565

    UniGene: Hs.189810