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SVBP Antibody

  • 货号：
    CSB-PA836653LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) SVBP Polyclonal antibody
  • Uniprot No.：
    Q8N300
  • 基因名：
    SVBP
  • 别名：
    SVBP antibody; CCDC23 antibody; Small vasohibin-binding protein antibody; Coiled coil domain-containing protein 23 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human Small vasohibin-binding protein (1-66AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，SVBP Antibody (CSB-PA836653LA01HU)，的标记方式是Non-conjugated。对于SVBP Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA836653LB01HU SVBP Antibody, HRP conjugated ELISA
    FITC CSB-PA836653LC01HU SVBP Antibody, FITC conjugated
    Biotin CSB-PA836653LD01HU SVBP Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Enhances the tyrosine carboxypeptidase activity of VASH1 and VASH2, thereby promoting the removal of the C-terminal tyrosine residue of alpha-tubulin. This activity is critical for spindle function and accurate chromosome segregation during mitosis since microtuble detyronisation regulates mitotic spindle length and postioning. Also required to enhance the solubility and secretion of VASH1 and VASH2. Plays a role in axon and excitatory synapse formation.
  • 基因功能参考文献：
    1. identified a novel UPS regulatory system in which essential domain architecture (VASH-PS) of VASHs, comprising regions VASH191-180 and VASH280-169 , regulate the cytosolic punctate structure formation in the absence of SVBP. PMID: 27879017
    2. VASH2 contributes to the angiogenesis in hepatocellular carcinoma via an SVBP-mediated paracrine mechanism. PMID: 22614011
    3. SVBP(CCDC23)acts as a secretory chaperone for VASH1. PMID: 20736312
  • 亚细胞定位：
    Cytoplasm. Secreted. Cytoplasm, cytoskeleton.
  • 蛋白家族：
    SVBP family
  • 数据库链接：

    HGNC: 29204

    OMIM: 617853

    KEGG: hsa:374969

    STRING: 9606.ENSP00000361599

    UniGene: Hs.113919