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SWD2 Antibody

  • 货号：
    CSB-PA339636XA01SVG
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Western Blot
      Positive WB detected in Recombinant protein
      All lanes: SWD2 antibody at 1:2000
      Secondary
      Goat polyclonal to rabbit IgG at 1/50000 dilution
      Predicted band size: 40.2 kDa
      Observed band size: 46 kDa
  • 其他：

产品详情

  • Uniprot No.：
    P36104
  • 基因名：
    SWD2
  • 别名：
    COMPASS component SWD2 (Complex proteins associated with SET1 protein SWD2) (Set1C component SWD2) SWD2 CPS35 SAF37 YKL018W
  • 反应种属：
    Bacteroides fragilis
  • 免疫原：
    Recombinant Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) SWD2 protein
  • 免疫原种属：
    Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
  • 标记方式：
    Non-conjugated
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    Protein G
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, WB
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    The COMPASS (Set1C) complex specifically mono-, di- and trimethylates histone H3 to form H3K4me1/2/3, which subsequently plays a role in telomere length maintenance and transcription elongation regulation.; Involved in mediating RNA polymerase II termination. Component of the cleavage and polyadenylation factor (CPF) complex, which plays a key role in polyadenylation-dependent pre-mRNA 3'-end formation and cooperates with cleavage factors including the CFIA complex and NAB4/CFIB. Component of the APT complex, which may be involved in polyadenylation-independent transcript 3'-end formation.
  • 基因功能参考文献：
    1. Swd2.2 opposes condensin-mediated chromosome condensation by facilitating the function of the two CPF-associated phosphatases PP1 and Ssu72. PMID: 24945319
    2. Ubiquitination of SWD2 links H2B ubiquitination to H3K4 trimethylation. PMID: 18849979
  • 亚细胞定位：
    Nucleus. Chromosome, telomere.
  • 蛋白家族：
    WD repeat SWD2 family
  • 数据库链接：

    KEGG: sce:YKL018W

    STRING: 4932.YKL018W