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TAF10 Antibody

  • 中文名称：
    TAF10兔多克隆抗体
  • 货号：
    CSB-PA247863
  • 规格：
    ￥1100
  • 图片：
    • The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using CSB-PA247863(TAF10 Antibody) at dilution 1/35, on the right is treated with synthetic peptide. (Original magnification: ×200)
    • The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA247863(TAF10 Antibody) at dilution 1/35, on the right is treated with synthetic peptide. (Original magnification: ×200)
    • Gel: 12%SDS-PAGE, Lysate: 40 μg, Lane: Human lung cancer tissue, Primary antibody: CSB-PA247863(TAF10 Antibody) at dilution 1/400, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 10 seconds
  • 其他：

产品详情

  • Uniprot No.：
    Q12962
  • 基因名：
    TAF10
  • 别名：
    TAF10 antibody; TAF2A antibody; TAF2H antibody; TAFII30 antibody; Transcription initiation factor TFIID subunit 10 antibody; STAF28 antibody; Transcription initiation factor TFIID 30 kDa subunit antibody; TAF(II)30 antibody; TAFII-30 antibody; TAFII30 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse
  • 免疫原：
    Synthetic peptide of Human TAF10
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen affinity purification
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,WB,IHC
  • 推荐稀释比：
    Application Recommended Dilution
    ELISA 1:2000-1:5000
    WB 1:500-1:2000
    IHC 1:25-1:100
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    TAFs are components of the transcription factor IID (TFIID) complex, PCAF histone acetylase complex and TBP-free TAFII complex (TFTC). TIIFD is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors.
  • 基因功能参考文献：
    1. Lysine oxidation of the transcription factor TAF10 by LOXL2 is a controlled protein modification and demonstrates a role for protein oxidation in regulating pluripotency genes. PMID: 25959397
    2. The carboxyl-terminal domain of the largest subunit of RNA polymerase II (pol II) comprises multiple tandem repeats of a heptapeptide. PMID: 20457598
    3. CDKN1C negatively regulates RNA polymerase II C-terminal domain phosphorylation in an E2F1-dependent manner PMID: 20106982
    4. TAF10 can be monomethylated by SET9-mediated methylation. PMID: 15099517
    5. novel role of three mammalian interacting partners in the nuclear localization of TAF10 PMID: 15870280
    6. TAFII30 was required for optimal P4 promoter activity and for the repressive association of estrogen receptor. PMID: 17599049

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  • 亚细胞定位：
    Nucleus.
  • 蛋白家族：
    TAF10 family
  • 数据库链接：

    HGNC: 11543

    OMIM: 600475

    KEGG: hsa:6881

    STRING: 9606.ENSP00000299424

    UniGene: Hs.5158