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TAF2 Antibody

  • 货号:
    CSB-PA747395LA01HU
  • 规格:
    ¥440
  • 促销:
    小规格抗体限时一口价
  • 图片:
    • Immunohistochemistry of paraffin-embedded human testis tissue using CSB-PA747395LA01HU at dilution of 1:100
  • 其他:

产品详情

  • 产品名称:
    Rabbit anti-Homo sapiens (Human) TAF2 Polyclonal antibody
  • Uniprot No.:
    Q6P1X5
  • 基因名:
    TAF2
  • 别名:
    TAF2 antibody; CIF150 antibody; TAF2B antibody; Transcription initiation factor TFIID subunit 2 antibody; 150 kDa cofactor of initiator function antibody; RNA polymerase II TBP-associated factor subunit B antibody; TBP-associated factor 150 kDa antibody; Transcription initiation factor TFIID 150 kDa subunit antibody; TAF(II)150 antibody; TAFII-150 antibody; TAFII150 antibody
  • 宿主:
    Rabbit
  • 反应种属:
    Human
  • 免疫原:
    Recombinant Human Transcription initiation factor TFIID subunit 2 protein (400-450AA)
  • 免疫原种属:
    Homo sapiens (Human)
  • 标记方式:
    Non-conjugated

    本页面中的产品,TAF2 Antibody (CSB-PA747395LA01HU),的标记方式是Non-conjugated。对于TAF2 Antibody,我们还提供其他标记。见下表:

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA747395LB01HU TAF2 Antibody, HRP conjugated ELISA
    FITC CSB-PA747395LC01HU TAF2 Antibody, FITC conjugated
    Biotin CSB-PA747395LD01HU TAF2 Antibody, Biotin conjugated ELISA
  • 克隆类型:
    Polyclonal
  • 抗体亚型:
    IgG
  • 纯化方式:
    >95%, Protein G purified
  • 浓度:
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式:
    Liquid
  • 应用范围:
    ELISA, IHC
  • 推荐稀释比:
    Application Recommended Dilution
    IHC 1:20-1:200
  • Protocols:
  • 储存条件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能:
    Transcription factor TFIID is one of the general factors required for accurate and regulated initiation by RNA polymerase II. TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors. It requires core promoter-specific cofactors for productive transcription stimulation. TAF2 stabilizes TFIID binding to core promoter.
  • 基因功能参考文献:
    1. the TAF2-TAF8-TAF10 complex demonstrates that there is a stepwise assembly pathway of nuclear holo-TFIID, regulated by nuclear import of preformed cytoplasmic submodules PMID: 25586196
    2. This study suggested that the Microcephaly thin corpus callosum intellectual disability syndrome is caused by the more conserved mutation p.Thr186Arg, with the second sequence change identified, p.Pro416His. PMID: 24084144
  • 相关疾病:
    Mental retardation, autosomal recessive 40 (MRT40)
  • 亚细胞定位:
    Nucleus.
  • 蛋白家族:
    TAF2 family
  • 组织特异性:
    Expressed in all tissues tested.
  • 数据库链接:

    HGNC: 11536

    OMIM: 604912

    KEGG: hsa:6873

    STRING: 9606.ENSP00000367406

    UniGene: Hs.122752