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TAF7L Antibody

  • 货号：
    CSB-PA688972LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • IHC image of CSB-PA688972LA01HU diluted at 1:300 and staining in paraffin-embedded human testis tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
    • Immunofluorescence staining of HepG2 cells with CSB-PA688972LA01HU at 1:100, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) TAF7L Polyclonal antibody
  • Uniprot No.：
    Q5H9L4
  • 基因名：
    TAF7L
  • 别名：
    TAF7L antibody; TAF2Q antibody; Transcription initiation factor TFIID subunit 7-like antibody; Cancer/testis antigen 40 antibody; CT40 antibody; RNA polymerase II TBP-associated factor subunit Q antibody; TATA box-binding protein-associated factor 50 kDa antibody; Transcription initiation factor TFIID 50 kDa subunit antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human Transcription initiation factor TFIID subunit 7-like protein (1-98AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，TAF7L Antibody (CSB-PA688972LA01HU)，的标记方式是Non-conjugated。对于TAF7L Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA688972LB01HU TAF7L Antibody, HRP conjugated ELISA
    FITC CSB-PA688972LC01HU TAF7L Antibody, FITC conjugated
    Biotin CSB-PA688972LD01HU TAF7L Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, IHC, IF
  • 推荐稀释比：
    Application Recommended Dilution
    IHC 1:200-1:500
    IF 1:50-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Probably functions as a spermatogenesis-specific component of the DNA-binding general transcription factor complex TFIID, a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors. May play a role in spermatogenesis.
  • 基因功能参考文献：
    1. Over-expression of TAF7L was observed in breast tumor cell lines. PMID: 26107214
    2. Frameshift mutations of TAF7L gene is associated with stomach and colorectal cancers. PMID: 25098277
    3. expression of AURKC, OIP5, PIWIL2 and TAF7L differed between patients with Acute myeloid leukemia, myelodysplastic syndrome and healthy controls in a gender-dependent manner PMID: 23292864
    4. TAF7L gene polymorphisms were found in male infertility patients and normal controls. PMID: 16597641
    5. The sequence variant in exon 13 of the TAF7L gene located on the X chromosome may represent a risk factor for spermatogenic failure. PMID: 17714218

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  • 亚细胞定位：
    Nucleus. Cytoplasm.
  • 蛋白家族：
    TAF7 family
  • 组织特异性：
    Testis-specific.
  • 数据库链接：

    HGNC: 11548

    OMIM: 300314

    KEGG: hsa:54457

    STRING: 9606.ENSP00000361998

    UniGene: Hs.223806