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TCEAL1 Antibody

  • 货号：
    CSB-PA004244
  • 规格：
    ￥880
  • 图片：
    • Western Blot analysis of COLO205 cells using TCEAL1 Polyclonal Antibody
  • 其他：

产品详情

  • Uniprot No.：
    Q15170
  • 基因名：
    TCEAL1
  • 别名：
    TCEAL1 antibody; SIIR antibody; Transcription elongation factor A protein-like 1 antibody; TCEA-like protein 1 antibody; Nuclear phosphoprotein p21/SIIR antibody; Transcription elongation factor S-II protein-like 1 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse,Rat
  • 免疫原：
    Synthesized peptide derived from the Internal region of Human TCEAL1.
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 抗体亚型：
    IgG
  • 纯化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 产品提供形式：
    Liquid
  • 应用范围：
    WB, IHC, ELISA
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:2000
    IHC 1:100-1:300
    IHC 1:200-1:1000
    ELISA 1:10000
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    May be involved in transcriptional regulation. Modulates various viral and cellular promoters in a promoter context-dependent manner. For example, transcription from the FOS promoter is increased, while Rous sarcoma virus (RSV) long terminal repeat (LTR) promoter activity is repressed. Does not bind DNA directly.
  • 基因功能参考文献：
    1. Treatment with active matabolite of vitamin D (1alpha,25-dihydroxyvitamin D3) up-regulates mRNA expression of p21. PMID: 19475409
    2. There was a marked decrease in the levels of the transcriptional elongation factor A gene in squamous cell cancer compared to normal samples. Reduced expression of the TCEAL1 gene may be important in esophageal squamous cell carcinogenesis. PMID: 15773840
  • 亚细胞定位：
    Nucleus.
  • 蛋白家族：
    TFS-II family, TFA subfamily
  • 组织特异性：
    Expressed in all tissues examined. Highly expressed in heart, ovary, prostate and skeletal muscle. Moderately expressed in brain, placenta, testis and small intestine. Weakly expressed in lung, liver and spleen. Expressed in several cancer cell lines.
  • 数据库链接：

    HGNC: 11616

    OMIM: 300237

    KEGG: hsa:9338

    UniGene: Hs.95243