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TCEB3 Antibody

  • 货号：
    CSB-PA551930
  • 规格：
    ￥2024
  • 图片：
    • Western blot analysis of extracts from Jurkat cells and HUVEC cells, using ELOA1 antibody.
    • Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue using ELOA1 antibody.
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) ELOA Polyclonal antibody
  • Uniprot No.：
    Q14241
  • 基因名：
    ELOA
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse,Rat
  • 免疫原：
    Synthesized peptide derived from internal of Human ELOA1.
  • 免疫原种属：
    Homo sapiens (Human)
  • 克隆类型：
    Polyclonal
  • 纯化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,WB,IHC
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:3000
    IHC 1:50-1:100
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    SIII, also known as elongin, is a general transcription elongation factor that increases the RNA polymerase II transcription elongation past template-encoded arresting sites. Subunit A is transcriptionally active and its transcription activity is strongly enhanced by binding to the dimeric complex of the SIII regulatory subunits B and C (elongin BC complex).
  • 基因功能参考文献：
    1. the Elongin A ubiquitin ligase and the CSB protein function together in a common pathway in response to Pol II stalling and DNA damage PMID: 28292928
    2. TCEB3C is a putative tumor suppressor gene of small intestinal neuroendocrine tumors PMID: 24351681
    3. Elongin A transcription elongation activity, but not its ubiquitination activity, is most important for its function in induction of transcription of ATF3 and p21. PMID: 23828199
  • 亚细胞定位：
    Nucleus.
  • 数据库链接：

    HGNC: 11620

    OMIM: 600786

    KEGG: hsa:6924

    STRING: 9606.ENSP00000395574

    UniGene: Hs.15535