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TCF19 Antibody

  • 中文名称：
    TCF19多克隆抗体
  • 货号：
    CSB-PA023295LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Western Blot
      Positive WB detected in: HL60 whole cell lysate
      All lanes: TCF19 antibody at 1:2000
      Secondary
      Goat polyclonal to rabbit IgG at 1/50000 dilution
      Predicted band size: 38 kDa
      Observed band size: 38 kDa
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) TCF19 Polyclonal antibody
  • Uniprot No.：
    Q9Y242
  • 基因名：
    TCF19
  • 别名：
    Transcription factor 19 (TCF-19) (Transcription factor SC1), TCF19, SC1
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human Transcription factor 19 protein (12-250aa)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，TCF19 Antibody (CSB-PA023295LA01HU)，的标记方式是Non-conjugated。对于TCF19 Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA023295LB01HU TCF19 Antibody, HRP conjugated ELISA
    FITC CSB-PA023295LC01HU TCF19 Antibody, FITC conjugated
    Biotin CSB-PA023295LD01HU TCF19 Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, WB
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:1000-1:5000
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Potential trans-activating factor that could play an important role in the transcription of genes required for the later stages of cell cycle progression.
  • 基因功能参考文献：
    1. Data suggest TCF19 interacts with histone 3 lysine 4 trimethylation through its plant homeodomain finger; TCF19 expression appears to regulate gluconeogenesis in hepatocytes; TCF19 interacts with CHD4 causing NuRD complex recruitment to gene promoters of enzymes involved in gluconeogenesis. (TCF19 = transcription factor 19; CHD4 = chromodomain helicase DNA binding protein 4; NuRD = nucleosome-remodeling-deacetylase) PMID: 29042441
    2. Genome association studies identified TCF19 as a new risk-associated loci for chronic hepatitis B on the HLA region of chromosome 6. PMID: 23760081
    3. Data shows increased apoptosis and susceptibility to endoplasmic reticulum (ER) stress after Tcf19 knockdown. PMID: 23860123
    4. Knockdown of Tcf19 reduces proliferation and increases apoptosis. Tcf19 is found in pancreatic islets in mouse and human. PMID: 23860123
    5. A linkage disequilibrium analysis established TCF19, POU5F1, CCHCR1 and PSORS1C1 as potential causal genes for the type 1 diabetes. PMID: 21076979

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  • 亚细胞定位：
    Nucleus.
  • 数据库链接：

    HGNC: 11629

    OMIM: 600912

    KEGG: hsa:6941

    STRING: 9606.ENSP00000365431

    UniGene: Hs.584807