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TCTN2 Antibody

  • 货号：
    CSB-PA023339GA01HU
  • 规格：
    ￥3,900
  • 其他：

产品详情

  • Uniprot No.：
    Q96GX1
  • 基因名：
    TCTN2
  • 别名：
    C12orf38 antibody; FLJ12975 antibody; MKS8 antibody; OTTHUMP00000239215 antibody; OTTHUMP00000239216 antibody; Tctn2 antibody; TECT2 antibody; TECT2_HUMAN antibody; Tectonic family member 2 antibody; Tectonic-2 antibody
  • 反应种属：
    Human,Mouse,Rat
  • 免疫原：
    Human TCTN2
  • 免疫原种属：
    Homo sapiens (Human)
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20oC, Avoid freeze / thaw cycles.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,IF,IP
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Component of the tectonic-like complex, a complex localized at the transition zone of primary cilia and acting as a barrier that prevents diffusion of transmembrane proteins between the cilia and plasma membranes. Required for hedgehog signaling transduction.
  • 基因功能参考文献：
    1. a truncating mutation in TCTN2 linked to Meckel Gruber syndrome was shown. PMID: 21462283
    2. Network building strategy led to the proposal of candidates for new ciliopathy disease genes, leading to the identification of the first human mutations in the Nephronophthisis gene Ataxin10 (ATXN10) and Joubert syndrome gene Tectonic2 (TCTN2). PMID: 21565611
  • 相关疾病：
    Meckel syndrome 8 (MKS8); Joubert syndrome 24 (JBTS24)
  • 亚细胞定位：
    Membrane; Single-pass type I membrane protein. Cytoplasm, cytoskeleton, cilium basal body.
  • 蛋白家族：
    Tectonic family
  • 数据库链接：

    HGNC: 25774

    OMIM: 613846

    KEGG: hsa:79867

    STRING: 9606.ENSP00000304941

    UniGene: Hs.167165