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TECPR2 Antibody

  • 货号：
    CSB-PA023369LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Immunohistochemistry of paraffin-embedded human pancreatic cancer using CSB-PA023369LA01HU at dilution of 1:100
    • Immunofluorescent analysis of PC-3 cells using CSB-PA023369LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) TECPR2 Polyclonal antibody
  • Uniprot No.：
    O15040
  • 基因名：
    TECPR2
  • 别名：
    TECPR2 antibody; KIAA0297 antibody; KIAA0329 antibody; Tectonin beta-propeller repeat-containing protein 2 antibody; WD repeat-containing protein KIAA0329/KIAA0297 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human Tectonin beta-propeller repeat-containing protein 2 protein (516-783AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，TECPR2 Antibody (CSB-PA023369LA01HU)，的标记方式是Non-conjugated。对于TECPR2 Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA023369LB01HU TECPR2 Antibody, HRP conjugated ELISA
    FITC CSB-PA023369LC01HU TECPR2 Antibody, FITC conjugated
    Biotin CSB-PA023369LD01HU TECPR2 Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, IHC, IF
  • 推荐稀释比：
    Application Recommended Dilution
    IHC 1:20-1:200
    IF 1:50-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Probably plays a role as positive regulator of autophagy.
  • 基因功能参考文献：
    1. Whole exome sequencing in an Italian pedigree suggests involvement of TECPR2 in a complex form of progressive motor neuron disease. PMID: 27406698
    2. The discovery of additional TECPR2 utations in non-Bukharian patients implies that this disease might be more common than previously appreciated PMID: 26542466
    3. Results show that TECPR2 associates with several trafficking components as SEC24D and cooperates with LC3C to regulate ER exit sites and ER export suggesting that TECPR2 functions as molecular scaffold linking early secretion pathway and autophagy. PMID: 26431026
    4. The discovered TECPR2 mutation implicates autophagy, a central intracellular mechanism, in spastic paraparesis. PMID: 23176824
  • 相关疾病：
    Spastic paraplegia 49, autosomal recessive (SPG49)
  • 蛋白家族：
    WD repeat KIAA0329 family
  • 组织特异性：
    Detected in skin fibroblast (at protein level).
  • 数据库链接：

    HGNC: 19957

    OMIM: 615000

    KEGG: hsa:9895

    STRING: 9606.ENSP00000352510

    UniGene: Hs.195667