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TENM3 Antibody

  • 货号：
    CSB-PA012753
  • 规格：
    ￥1100
  • 图片：
    • The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using CSB-PA012753(TENM3 Antibody) at dilution 1/50, on the right is treated with synthetic peptide. (Original magnification: ×200)
    • The image on the left is immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using CSB-PA012753(TENM3 Antibody) at dilution 1/50, on the right is treated with synthetic peptide. (Original magnification: ×200)
  • 其他：

产品详情

  • Uniprot No.：
    Q9P273
  • 基因名：
    TENM3
  • 别名：
    FLJ10474 antibody; FLJ10886 antibody; KIAA1455 antibody; odd Oz Ten m homolog 3 antibody; odz odd Oz ten m homolog 3 (Drosophila) antibody; odz odd Oz ten m homolog 3 antibody; ODZ3 like protein antibody; Protein Odd Oz ten m homolog 3 antibody; Protein Odd Oz/ten-m homolog 3 antibody; Ten 3 antibody; Ten M3 antibody; Ten-3 antibody; Ten-m3 antibody; TEN3_HUMAN antibody; Tenascin M3 antibody; Tenascin-M3 antibody; Teneurin 3 antibody; Teneurin transmembrane protein 3 antibody; Teneurin-3 antibody; Teneurin3 antibody; tenm3 antibody; TNM3 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse
  • 免疫原：
    Synthetic peptide of Human TENM3
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen affinity purification
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,IHC
  • 推荐稀释比：
    Application Recommended Dilution
    ELISA 1:3000-1:10000
    IHC 1:50-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Involved in neural development by regulating the establishment of proper connectivity within the nervous system. Acts in both pre- and postsynaptic neurons in the hippocampus to control the assembly of a precise topographic projection: required in both CA1 and subicular neurons for the precise targeting of proximal CA1 axons to distal subiculum, probably by promoting homophilic cell adhesion. Required for proper dendrite morphogenesis and axon targeting in the vertebrate visual system, thereby playing a key role in the development of the visual pathway. Regulates the formation in ipsilateral retinal mapping to both the dorsal lateral geniculate nucleus (dLGN) and the superior colliculus (SC). May also be involved in the differentiation of the fibroblast-like cells in the superficial layer of mandibular condylar cartilage into chondrocytes.
  • 基因功能参考文献：
    1. This report supports the association of TENM3 mutations with colobomatous microphthalmia and expands the phenotypic spectrum associated with mutations in this gene PMID: 27103084
    2. Null mutation in ODZ3 causes autosomal recessive microphthalmia in humans. PMID: 22766609
  • 相关疾病：
    Microphthalmia, isolated, with coloboma, 9 (MCOPCB9)
  • 亚细胞定位：
    Cell membrane; Single-pass membrane protein. Cell projection, axon.
  • 蛋白家族：
    Tenascin family, Teneurin subfamily
  • 组织特异性：
    Expressed in adult and fetal brain, slightly lower levels in testis and ovary, and intermediate levels in all other peripheral tissues examined. Not expressed in spleen or liver. Expression was high in brain, with highest levels in amygdala and caudate nu
  • 数据库链接：

    HGNC: 29944

    OMIM: 610083

    KEGG: hsa:55714

    STRING: 9606.ENSP00000385276

    UniGene: Hs.130438