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TERB1 Antibody

  • 货号：
    CSB-PA822742LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Immunohistochemistry of paraffin-embedded human ovarian cancer using CSB-PA822742LA01HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human prostata cancer using CSB-PA822742LA01HU at dilution of 1:100
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) TERB1 Polyclonal antibody
  • Uniprot No.：
    Q8NA31
  • 基因名：
    TERB1
  • 别名：
    TERB1 antibody; CCDC79 antibody; Telomere repeats-binding bouquet formation protein 1 antibody; Coiled-coil domain-containing protein 79 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human Telomere repeats-binding bouquet formation protein 1 protein (301-550AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，TERB1 Antibody (CSB-PA822742LA01HU)，的标记方式是Non-conjugated。对于TERB1 Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA822742LB01HU TERB1 Antibody, HRP conjugated ELISA
    FITC CSB-PA822742LC01HU TERB1 Antibody, FITC conjugated
    Biotin CSB-PA822742LD01HU TERB1 Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, IHC
  • 推荐稀释比：
    Application Recommended Dilution
    IHC 1:20-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Meiosis-specific telomere-associated protein involved in meiotic telomere attachment to the nucleus inner membrane, a crucial step for homologous pairing and synapsis. Component of the MAJIN-TERB1-TERB2 complex, which promotes telomere cap exchange by mediating attachment of telomeric DNA to the inner nuclear membrane and replacement of the protective cap of telomeric chromosomes: in early meiosis, the MAJIN-TERB1-TERB2 complex associates with telomeric DNA and the shelterin/telosome complex. During prophase, the complex matures and promotes release of the shelterin/telosome complex from telomeric DNA. In the MAJIN-TERB1-TERB2 complex, TERB1 probably mediates association with the shelterin/telosome complex via interaction with TERF1, promoting priming telomeric DNA attachment'. Promotes telomere association with the nuclear envelope and deposition of the SUN-KASH/LINC complex. Also recruits cohesin to telomeres to develop structural rigidity.
  • 亚细胞定位：
    Chromosome, telomere. Nucleus inner membrane.
  • 蛋白家族：
    TERB1 family
  • 数据库链接：

    HGNC: 26675

    OMIM: 617332

    KEGG: hsa:283847

    STRING: 9606.ENSP00000462883

    UniGene: Hs.376505