TMEM108 Antibody
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货号:CSB-PA023677GA01HU
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规格:¥3,900
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其他:
产品详情
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Uniprot No.:Q6UXF1
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基因名:TMEM108
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别名:TMEM108 antibody; KIAA1690 antibody; RTLN antibody; UNQ1875/PRO4318 antibody; Transmembrane protein 108 antibody; Retrolinkin antibody
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宿主:Rabbit
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反应种属:Human
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免疫原:Human TMEM108
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免疫原种属:Homo sapiens (Human)
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抗体亚型:IgG
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纯化方式:Antigen Affinity purified
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浓度:It differs from different batches. Please contact us to confirm it.
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保存缓冲液:PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
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产品提供形式:Liquid
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应用范围:ELISA,WB
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Protocols:
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储存条件:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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货期:Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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靶点详情
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功能:Transmembrane protein required for proper cognitive functions. Involved in the development of dentate gyrus (DG) neuron circuitry, is necessary for AMPA receptors surface expression and proper excitatory postsynaptic currents of DG granule neurons. Regulates the organization and stability of the microtubule network of sensory neurons to allow axonal transport. Through the interaction with DST, mediates the docking of the dynein/dynactin motor complex to vesicle cargos for retrograde axonal transport. In hippocampal neurons, required for BDNF-dependent dendrite outgrowth. Cooperates with SH3GL2 and recruits the WAVE1 complex to facilitate actin-dependent BDNF:NTRK2 early endocytic trafficking and mediate signaling from early endosomes.
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亚细胞定位:Membrane; Multi-pass membrane protein. Cell junction, synapse, postsynaptic density. Endosome membrane. Cell projection, axon. Cell projection, dendrite. Early endosome.
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数据库链接:
HGNC: 28451
OMIM: 617361
KEGG: hsa:66000
STRING: 9606.ENSP00000324651
UniGene: Hs.191616
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