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TMEM205 Antibody

  • 货号：
    CSB-PA023799LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Immunohistochemistry of paraffin-embedded human adrenal gland tissue using CSB-PA023799LA01HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human pancreatic tissue using CSB-PA023799LA01HU at dilution of 1:100
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) TMEM205 Polyclonal antibody
  • Uniprot No.：
    Q6UW68
  • 基因名：
    TMEM205
  • 别名：
    TMEM205; UNQ501/PRO1018; Transmembrane protein 205
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human Transmembrane protein 205 protein (104-153AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，TMEM205 Antibody (CSB-PA023799LA01HU)，的标记方式是Non-conjugated。对于TMEM205 Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA023799LB01HU TMEM205 Antibody, HRP conjugated ELISA
    FITC CSB-PA023799LC01HU TMEM205 Antibody, FITC conjugated
    Biotin CSB-PA023799LD01HU TMEM205 Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, IHC
  • 推荐稀释比：
    Application Recommended Dilution
    IHC 1:20-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    In cancer cells, plays a role in resistance to the chemotherapeutic agent cisplatin.
  • 基因功能参考文献：
    1. The genetic polymorphisms in OCT2, AQP2, AQP9 and TMEM205 may contribute to chemotherapy response in lung cancer patients. PMID: 24643204
    2. Results indicate that a novel mechanism for cisplatin resistance is mediated by TMEM205 overexpression. PMID: 20589834
  • 亚细胞定位：
    Membrane; Multi-pass membrane protein. Note=Located on cell surface microvilli. In cancer cells, transition in subcellular location from cell surface to intracellular regions correlates the progression of cisplatin resistance.
  • 蛋白家族：
    TMEM205 family
  • 组织特异性：
    Widely expressed with highest levels in pancreas, followed by adrenal gland, thyroid, liver, mammary gland, prostate, kidney, and retina; lowest levels in skeletal muscle. Overexpressed in cisplatin-resistant cancer cells (at protein level).
  • 数据库链接：

    HGNC: 29631

    OMIM: 613771

    KEGG: hsa:374882

    STRING: 9606.ENSP00000346954

    UniGene: Hs.737060