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TMEM47 Antibody

  • 货号：
    CSB-PA023845LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Immunofluorescent analysis of U251 cells using CSB-PA023845LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
    • Immunohistochemistry analysis of human brain tissue using CSB-PA023845LA01HU at dilution of 1:100
    • Immunofluorescent analysis of Hela cells using CSB-PA023845LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) TMEM47 Polyclonal antibody
  • Uniprot No.：
    Q9BQJ4
  • 基因名：
    TMEM47
  • 别名：
    TMEM47; BCMP1; TM4SF10; Transmembrane protein 47; Brain cell membrane protein 1; Transmembrane 4 superfamily member 10
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human Transmembrane protein 47 protein (42-82AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，TMEM47 Antibody (CSB-PA023845LA01HU)，的标记方式是Non-conjugated。对于TMEM47 Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA023845LB01HU TMEM47 Antibody, HRP conjugated ELISA
    FITC CSB-PA023845LC01HU TMEM47 Antibody, FITC conjugated
    Biotin CSB-PA023845LD01HU TMEM47 Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, IHC, IF
  • 推荐稀释比：
    Application Recommended Dilution
    IHC 1:20-1:200
    IF 1:50-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Regulates cell junction organization in epithelial cells. May play a role in the transition from adherens junction to tight junction assembly. May regulate F-actin polymerization required for tight junctional localization dynamics and affect the junctional localization of PARD6B. During podocyte differentiation may negatively regulate activity of FYN and subsequently the abundance of nephrin.
  • 基因功能参考文献：
    1. TM4SF10, possibly through ADAP, may regulate Fyn activity PMID: 21881001
    2. Single nucleotide polymorphisms, but no disease-associated mutations, were identified in X-linked mental retardation patients. PMID: 15345028
    3. A 4-transmembrane protein, related to PMP22/EMPs and the Claudins, localizes to the plasma membrane and the ER. The mRNA is present in high amounts in brain. PMID: 11472633
  • 亚细胞定位：
    Membrane; Multi-pass membrane protein. Cell junction, adherens junction.
  • 蛋白家族：
    TMEM47 family
  • 组织特异性：
    Expressed in adult brain, fetal brain, cerebellum, heart, lung, prostate and thyroid.
  • 数据库链接：

    HGNC: 18515

    OMIM: 300698

    KEGG: hsa:83604

    UniGene: Hs.8769