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TMEM98 Antibody

  • 货号：
    CSB-PA023901LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) TMEM98 Polyclonal antibody
  • Uniprot No.：
    Q9Y2Y6
  • 基因名：
    TMEM98
  • 别名：
    TMEM98 antibody; UNQ536/PRO1079 antibody; Transmembrane protein 98 antibody; Protein TADA1 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human Transmembrane protein 98 protein (25-226AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，TMEM98 Antibody (CSB-PA023901LA01HU)，的标记方式是Non-conjugated。对于TMEM98 Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA023901LB01HU TMEM98 Antibody, HRP conjugated ELISA
    FITC CSB-PA023901LC01HU TMEM98 Antibody, FITC conjugated
    Biotin CSB-PA023901LD01HU TMEM98 Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Functions as a negative regulator of MYRF in oligodendrocyte differentiation and myelination. Interacts with the C-terminal of MYRF inhibiting MYRF self-cleavage and N-fragment nuclear translocation. The secreted form promotes differentiation of T helper 1 cells (Th1).
  • 基因功能参考文献：
    1. siRNA-TMEM98 inhibited the invasion and migration of non-small cell lung cancer cells. PMID: 26884835
    2. Two novel TMEM98 mutations have been found in two pedigrees with autosomal dominant nanophthalmos. PMID: 26392740
    3. we identified a panel of novel common chemoresistance-associated genes and demonstrated that TMEM98 is a chemoresistance-conferring gene in hepatocellular carcinoma. PMID: 24608572
    4. A novel gene associated with nanophthalmos, TMEM98 most likely represents the cause of the disease. PMID: 24852644
  • 相关疾病：
    Nanophthalmos 4 (NNO4)
  • 亚细胞定位：
    Cell membrane; Single-pass type II membrane protein. Secreted. Secreted, extracellular exosome. Endoplasmic reticulum membrane; Single-pass type II membrane protein.
  • 蛋白家族：
    TMEM98 family
  • 组织特异性：
    Widely expressed with high expression in the ovary, pancreas and prostate. Expressed in the eye, particularly in corneal endothelium, iris, ciliary body, sclera, optic nerve, optic nerve head, and retina. Expressed by activated peripheral blood mononuclea
  • 数据库链接：

    HGNC: 24529

    OMIM: 615949

    KEGG: hsa:26022

    STRING: 9606.ENSP00000378138

    UniGene: Hs.3447