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TP53INP2 Antibody

  • 货号：
    CSB-PA117430
  • 规格：
    ￥2024
  • 图片：
    • Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using TP53INP2 antibody.
    • Immunofluorescence analysis of MCF-7 cells, using TP53INP2 antibody.
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Mus musculus (Mouse) Tp53inp2 Polyclonal antibody
  • Uniprot No.：
    Q8CFU8
  • 基因名：
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse
  • 免疫原：
    Synthesized peptide derived from internal of Human TP53INP2.
  • 免疫原种属：
    Mus musculus (Mouse)
  • 克隆类型：
    Polyclonal
  • 纯化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,IHC,IF
  • 推荐稀释比：
    Application Recommended Dilution
    IHC 1:50-1:100
    IF 1:100-1:500
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Dual regulator of transcription and autophagy. Positively regulates autophagy and is required for autophagosome formation and processing. May act as a scaffold protein that recruits MAP1LC3A, GABARAP and GABARAPL2 and brings them to the autophagosome membrane by interacting with VMP1 where, in cooperation with the BECN1-PI3-kinase class III complex, they trigger autophagosome development. Acts as a transcriptional activator of THRA.
  • 基因功能参考文献：
    1. TP53INP2 repression is part of an adaptive mechanism aimed at preserving muscle mass under conditions in which insulin action is deficient. PMID: 24713655
  • 亚细胞定位：
    Cytoplasm, cytosol. Nucleus. Nucleus, PML body. Cytoplasmic vesicle, autophagosome.
  • 数据库链接：

    KEGG: mmu:68728

    STRING: 10090.ENSMUSP00000037627

    UniGene: Mm.293605