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TPSB2 Antibody

  • 货号：
    CSB-PA024128LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Immunohistochemistry of paraffin-embedded human testis tissue using CSB-PA024128LA01HU at dilution of 1:100
    • Western Blot
      Positive WB detected in: Rat liver tissue, Rat kidney tissue, Mouse liver tissue, Mouse kidney tissue, Mouse stomach tissue
      All lanes: TPSB2 antibody at 3µg/ml
      Secondary
      Goat polyclonal to rabbit IgG at 1/50000 dilution
      Predicted band size: 31 kDa
      Observed band size: 31 kDa
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) TPSB2 Polyclonal antibody
  • Uniprot No.：
    P20231
  • 基因名：
    TPSB2
  • 别名：
    Mast cell tryptase beta II antibody; Mast cell tryptase beta III antibody; TPS2 antibody; TPSB2 antibody; TRYB2_HUMAN antibody; Tryptase beta 2 (gene/pseudogene) antibody; Tryptase beta-2 antibody; Tryptase II antibody; Tryptase-2 antibody; TryptaseB antibody; TryptaseC antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human, Mouse, Rat
  • 免疫原：
    Recombinant Human Tryptase beta-2 protein (31-275AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，TPSB2 Antibody (CSB-PA024128LA01HU)，的标记方式是Non-conjugated。对于TPSB2 Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA024128LB01HU TPSB2 Antibody, HRP conjugated ELISA
    FITC CSB-PA024128LC01HU TPSB2 Antibody, FITC conjugated
    Biotin CSB-PA024128LD01HU TPSB2 Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, WB, IHC
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:5000
    IHC 1:20-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Tryptase is the major neutral protease present in mast cells and is secreted upon the coupled activation-degranulation response of this cell type. May play a role in innate immunity.
  • 基因功能参考文献：
    1. These observations indicate that betaII-tryptase activity is post-translationally regulated by an allosteric disulfide bond. PMID: 24142694
    2. Results indicate a key role for heparin in the activation of human betaI- and beta2-tryptase. PMID: 15567416
    3. The disease severity and plasma tryptase levels were not affected by the number of alpha or beta tryptase alleles in mastocytosis patients. PMID: 17449330
    4. Strong linkage of TPSAB1 and TPSB2 and pairing of deficiency alleles with functional alleles in observed haplotypes protect human subjects from "knockout" genomes and indeed from inheritance of fewer than 2 active alleles. PMID: 19748655
  • 亚细胞定位：
    Secreted. Note=Released from the secretory granules upon mast cell activation.
  • 蛋白家族：
    Peptidase S1 family, Tryptase subfamily
  • 数据库链接：

    HGNC: 14120

    OMIM: 191081

    KEGG: hsa:64499

    UniGene: Hs.405479