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TRMT1 Antibody

  • 货号：
    CSB-PA024536GA01HU
  • 规格：
    ￥3,900
  • 其他：

产品详情

  • Uniprot No.：
    Q9NXH9
  • 基因名：
  • 别名：
    2)G26)dimethyltransferase antibody; 2-dimethylguanosine-26 methyltransferase antibody; FLJ20244 antibody; N(2) N(2) dimethylguanosine tRNA methyltransferase antibody; N(2)-N(2)) methyltransferase antibody; TRM 1 antibody; TRM1 tRNA methyltransferase 1 homolog antibody; TRM1_HUMAN antibody; TRMT 1 antibody; Trmt1 antibody; tRNA (guanine(26)-N(2))-dimethyltransferase antibody; tRNA 2 2 dimethylguanosine 26 methyltransferase antibody; tRNA 2 antibody; tRNA(guanine 26 N(2) N(2)) methyltransferase antibody; tRNA(guanine-26 antibody; tRNA(m(2 2)G26)dimethyltransferase antibody; tRNA(m(2 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse,Rat
  • 免疫原：
    Human TRMT1
  • 免疫原种属：
    Homo sapiens (Human)
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,WB,IHC
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Dimethylates a single guanine residue at position 26 of most tRNAs using S-adenosyl-L-methionine as donor of the methyl groups.
  • 基因功能参考文献：
    1. Results uncover a biological role for TRMT1-catalyzed tRNA modification in redox metabolism and show that individuals with TRMT1-associated ID are likely to have major perturbations in cellular homeostasis due to the lack of m2,2G modifications. PMID: 28784718
    2. a missense variant was found in GRM1 gene, while in the second family, a frameshift alteration was identified in TRMT1, both of which were found to co-segregate with the intellectual disability. PMID: 26308914
  • 蛋白家族：
    Class I-like SAM-binding methyltransferase superfamily, Trm1 family
  • 数据库链接：

    HGNC: 25980

    OMIM: 611669

    KEGG: hsa:55621

    STRING: 9606.ENSP00000350352

    UniGene: Hs.515169