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TSGA10 Antibody

  • 货号：
    CSB-PA025126GA01HU
  • 规格：
    ￥3,900
  • 其他：

产品详情

  • Uniprot No.：
    Q9BZW7
  • 基因名：
    TSGA10
  • 别名：
    Cancer/testis antigen 79 antibody; CEP4L antibody; CT79 antibody; Predicted testis protein antibody; Testis development protein NYD-SP7 antibody; Testis-specific gene 10 protein antibody; Testis-specific protein 10 antibody; TSG10_HUMAN antibody; Tsga10 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse,Rat
  • 免疫原：
    Human TSGA10
  • 免疫原种属：
    Homo sapiens (Human)
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity Purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,WB
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Plays a role in spermatogenesis. When overexpressed, prevents nuclear localization of HIF1A.
  • 基因功能参考文献：
    1. TSGA10 tends to express variants with shorter 5'UTR. PMID: 28739310
    2. Overexpression of TSGA10 would induce disruption of HIF-1alpha axis and exert potent inhibitory effects on tumor angiogenesis and metastasis. PMID: 26573430
    3. Report role for mir-577/TSGA10 axis in regulation esophageal squamous cell carcinoma progression. PMID: 24294352
    4. TSGA10 should be considered as an autoantigen in a subset of autoimmune polyendocrine syndrome type 1 patients and also in a minority of systemic lupus erythematosus patients PMID: 21198756
    5. TSGA10 could influence the function of antigen presenting cells via its interaction with cytoskeletal proteins such as vimentin PMID: 20797700
    6. over-expressed in 4 of 20 hepatocellular carcinomas (HCC), 1 of 20 colon cancers, 7 of 20 ovarian cancers, 3 of 20 prostate cancers, 1 of 21 malignant melanomas, and 8 of 21 bladder cancers PMID: 15107545
    7. The RT-PCR of TSGA10 expression may help in detection of residual clonal cells leading to early diagnosis and better prognostic qualification of the acute lymphoblastic leukemia. PMID: 16406020
    8. TSGA10 is target of immune reactions in Autoimmune polyendocrine syndrome type 1 (APS1). PMID: 18000009

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  • 亚细胞定位：
    Cytoplasm. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole.
  • 蛋白家族：
    CEP135/TSGA10 family
  • 组织特异性：
    Expressed in the testis, in spermatozoa (at protein level). Expressed in actively dividing fetal tissues, including sternum, intestine, limb, kidney and stomach.
  • 数据库链接：

    HGNC: 14927

    OMIM: 607166

    KEGG: hsa:80705

    STRING: 9606.ENSP00000347161

    UniGene: Hs.120267