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TSHZ1 Antibody

  • 货号：
    CSB-PA006423
  • 规格：
    ￥880
  • 其他：

产品详情

  • Uniprot No.：
    Q6ZSZ6
  • 基因名：
    TSHZ1
  • 别名：
    TSHZ1 antibody; SDCCAG33 antibody; TSH1 antibody; Teashirt homolog 1 antibody; Antigen NY-CO-33 antibody; Serologically defined colon cancer antigen 33 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse
  • 免疫原：
    Synthesized peptide derived from the C-terminal region of Human TSHZ1.
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 抗体亚型：
    IgG
  • 纯化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 产品提供形式：
    Liquid
  • 应用范围：
    IHC, ELISA
  • 推荐稀释比：
    Application Recommended Dilution
    IHC 1:100-1:300
    ELISA 1:20000
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Probable transcriptional regulator involved in developmental processes. May act as a transcriptional repressor (Potential).
  • 基因功能参考文献：
    1. TSHZ1 levels are reduced in human islets of donors with type 2 diabetes PMID: 25918232
    2. TSHZ1 is a key regulator of mammalian olfactory bulb development and function and controls the expression of PROKR2. PMID: 24487590
    3. Together, these results demonstrate that hemizygosity of TSHZ1 leads to congenital aural atresia as a result of haploinsufficiency PMID: 22152683
    4. a significant up-regulation of BORIS (p<0.001) and TSHZ1 transcripts (p<0.05) for JAs compared to nasal mucosa. PMID: 21874228
    5. This publication characterizes the mouse ortholog of the human teashirt zinc finger homeobox 1 gene and proposes that the human gene may be a candidate gene for CAA syndrome. PMID: 17586487

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  • 相关疾病：
    Aural atresia, congenital (CAA)
  • 亚细胞定位：
    Nucleus.
  • 蛋白家族：
    Teashirt C2H2-type zinc-finger protein family
  • 组织特异性：
    Expressed in brain; strongly reduced in post-mortem elderly subjects with Alzheimer disease.
  • 数据库链接：

    HGNC: 10669

    OMIM: 607842

    KEGG: hsa:10194

    STRING: 9606.ENSP00000323584

    UniGene: Hs.284217