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TUBB6 Antibody

  • 货号：
    CSB-PA880105LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Western blot
      All lanes: TUBB6 antibody at 4μg/ml
      Lane 1: Hela whole cell lysate
      Lane 2: MDA-MB-231 whole cell lysate
      Secondary
      Goat polyclonal to rabbit IgG at 1/10000 dilution
      Predicted band size: 50 kDa
      Observed band size: 50 kDa
    • Immunohistochemistry of paraffin-embedded human colon cancer using CSB-PA880105LA01HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human prostate cancer using CSB-PA880105LA01HU at dilution of 1:100
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) TUBB6 Polyclonal antibody
  • Uniprot No.：
    Q9BUF5
  • 基因名：
  • 别名：
    tubulin beta-6 chain-like antibody; class V beta-tubulin antibody; HsT1601 antibody; TBB6_HUMAN antibody; TUBB-5 antibody; TUBB6 antibody; Tubulin beta 6 chain antibody; tubulin beta 6 class V antibody; tubulin beta class V antibody; tubulin beta MGC4083 antibody; Tubulin beta-6 antibody; Tubulin beta-6 chain antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human Tubulin beta-6 chain protein (1-446AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，TUBB6 Antibody (CSB-PA880105LA01HU)，的标记方式是Non-conjugated。对于TUBB6 Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA880105LB01HU TUBB6 Antibody, HRP conjugated ELISA
    FITC CSB-PA880105LC01HU TUBB6 Antibody, FITC conjugated
    Biotin CSB-PA880105LD01HU TUBB6 Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, WB, IHC
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:2000
    IHC 1:20-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.
  • 基因功能参考文献：
    1. Findings enlarge the spectrum of tubulinopathies and emphasize that mutations of TUBB6 should be considered in patients with congenital non-progressive facial palsy. PMID: 29016863
    2. TUBB6 is an inhibitor of pyroptosis. PMID: 24173717
    3. Data indicate that leucine-rich repeat kinase 2 (LRRK2) selectively interacts with three beta-tubulin isoforms: TUBB, TUBB4, and TUBB6. PMID: 24275654
    4. betaV-tubulin expression is a potentially promising prognostic marker of malignancy. PMID: 22903939
    5. in colorectal cancer patients, there was a link between poor survival, the expression of TUBB3/TUBB6, and androgen receptor only in females PMID: 22438565
    6. The TUBB6 expression was largely decreased in most tumors. PMID: 20191564

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  • 亚细胞定位：
    Cytoplasm, cytoskeleton.
  • 蛋白家族：
    Tubulin family
  • 组织特异性：
    Ubiquitous. Maximal expression in breast and lung, where it represents around 10% of all beta-tubulins. Largely decreased expression in most cancerous tissues.
  • 数据库链接：

    HGNC: 20776

    OMIM: 615103

    KEGG: hsa:84617

    STRING: 9606.ENSP00000318697

    UniGene: Hs.193491