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TULP3 Antibody

  • 货号：
    CSB-PA025348LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Immunohistochemistry of paraffin-embedded human testis tissue using CSB-PA025348LA01HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human colon cancer using CSB-PA025348LA01HU at dilution of 1:100
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) TULP3 Polyclonal antibody
  • Uniprot No.：
    O75386
  • 基因名：
    TULP3
  • 别名：
    MGC45295 antibody; Tubby like protein 3 antibody; Tubby related protein 3 antibody; Tubby-like protein 3 antibody; Tubby-related protein 3 antibody; TUBL 3 antibody; TUBL3 antibody; TULP 3 antibody; TULP3 antibody; TULP3_HUMAN antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human Tubby-related protein 3 protein (1-260AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，TULP3 Antibody (CSB-PA025348LA01HU)，的标记方式是Non-conjugated。对于TULP3 Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA025348LB01HU TULP3 Antibody, HRP conjugated ELISA
    FITC CSB-PA025348LC01HU TULP3 Antibody, FITC conjugated
    Biotin CSB-PA025348LD01HU TULP3 Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, IHC
  • 推荐稀释比：
    Application Recommended Dilution
    IHC 1:20-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Negative regulator of the Shh signaling transduction pathway: recruited to primary cilia via association with the IFT complex A (IFT-A) and is required for recruitment of G protein-coupled receptor GPR161 to cilia, a promoter of PKA-dependent basal repression machinery in Shh signaling. Binds to phosphorylated inositide (phosphoinositide) lipids. Both IFT-A- and phosphoinositide-binding properties are required to regulate ciliary G protein-coupled receptor trafficking. Not involved in ciliogenesis. During adipogenesis, regulates ciliary trafficking of FFAR4 in preadipocytes.
  • 基因功能参考文献：
    1. Data demonstrated that pancreatic cancer patients exhibiting high transcriptional levels of TULP3 showed a poor overall survival rate. PMID: 24668219
  • 亚细胞定位：
    Nucleus. Cell membrane. Cell projection, cilium. Cytoplasm. Secreted.
  • 蛋白家族：
    TUB family
  • 组织特异性：
    Expressed at high levels in testis, ovaries, thyroid, and spinal chord.
  • 数据库链接：

    HGNC: 12425

    OMIM: 604730

    KEGG: hsa:7289

    STRING: 9606.ENSP00000380321

    UniGene: Hs.655333