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TXNL4A Antibody

  • 货号：
    CSB-PA025386LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Immunofluorescent analysis of PC-3 cells using CSB-PA025386LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) TXNL4A Polyclonal antibody
  • Uniprot No.：
    P83876
  • 基因名：
    TXNL4A
  • 别名：
    TXNL4A antibody; DIM1 antibody; TXNL4Thioredoxin-like protein 4A antibody; DIM1 protein homolog antibody; Spliceosomal U5 snRNP-specific 15 kDa protein antibody; Thioredoxin-like U5 snRNP protein U5-15kD antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human Thioredoxin-like protein 4A protein (1-142AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，TXNL4A Antibody (CSB-PA025386LA01HU)，的标记方式是Non-conjugated。对于TXNL4A Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA025386LB01HU TXNL4A Antibody, HRP conjugated ELISA
    FITC CSB-PA025386LC01HU TXNL4A Antibody, FITC conjugated
    Biotin CSB-PA025386LD01HU TXNL4A Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, IF
  • 推荐稀释比：
    Application Recommended Dilution
    IF 1:50-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Plays role in pre-mRNA splicing as component of the U5 snRNP and U4/U6-U5 tri-snRNP complexes that are involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex).
  • 基因功能参考文献：
    1. Recessive variants in TXNL4A were identified in two individuals with Burn-McKeown syndrome as well as in three individuals (from two families) with isolated choanal atresia. PMID: 28905882
    2. Reporter gene and in vivo assays showed that the promoter deletions led to reduced expression of TXNL4A. Depletion of TXNL4A (Dib1) in yeast demonstrated reduced assembly of the tri-snRNP complex. PMID: 25434003
    3. human dim1 is a peptidase with autocleavage activity that results in a thioredoxin-like core PMID: 17177886
  • 相关疾病：
    Burn-McKeown syndrome (BMKS)
  • 亚细胞定位：
    Nucleus.
  • 蛋白家族：
    DIM1 family
  • 数据库链接：

    HGNC: 30551

    OMIM: 608572

    KEGG: hsa:10907

    STRING: 9606.ENSP00000269601

    UniGene: Hs.465498