Tmprss4 Antibody
产品详情
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产品名称:Rabbit anti-Mus musculus (Mouse) Tmprss4 Polyclonal antibody
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Uniprot No.:Q8VCA5
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基因名:Tmprss4
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别名:Tmprss4 antibody; Cap2 antibody; Transmembrane protease serine 4 antibody; EC 3.4.21.- antibody; Channel-activating protease 2 antibody; mCAP2 antibody
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宿主:Rabbit
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反应种属:Mouse
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免疫原:Recombinant Mouse Transmembrane protease serine 4 protein (52-435AA)
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免疫原种属:Mus musculus (Mouse)
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标记方式:Non-conjugated
本页面中的产品,Tmprss4 Antibody (CSB-PA844988LA01MO),的标记方式是Non-conjugated。对于Tmprss4 Antibody,我们还提供其他标记。见下表:
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克隆类型:Polyclonal
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抗体亚型:IgG
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纯化方式:>95%, Protein G purified
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浓度:It differs from different batches. Please contact us to confirm it.
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保存缓冲液:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 -
产品提供形式:Liquid
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应用范围:ELISA
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Protocols:
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储存条件:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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货期:Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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靶点详情
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功能:Plasma membrane-anchored serine protease that directly induces processing of pro-uPA/PLAU into the active form through proteolytic activity. Seems to be capable of activating ENaC.
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基因功能参考文献:
- The lung fibrotic response evaluated at 28 days after bleomycin injury was markedly attenuated in the haplodeficient and deficient TMPRSS4 mice. PMID: 29529050
- Epithelial Sodium Channel-Mediated Sodium Transport Is Not Dependent on the Membrane-Bound Serine Protease CAP2/Tmprss4 PMID: 26309024
- Progression and metastatic potential of several cancers is concordant with an increased expression of TMPRSS4. PMID: 22944691
- TMPRSS4 primarily activates ENaC by cleaving basic residues within the tract gammaK173-K186 distal to the furin cleavage site, thereby releasing a previously defined key inhibitory tract encompassing gammaR158-F168 from the gamma-subunit. PMID: 21993886
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亚细胞定位:Cell membrane; Single-pass type II membrane protein.; [Transmembrane protease serine 4 catalytic chain]: Secreted.
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蛋白家族:Peptidase S1 family
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数据库链接:
KEGG: mmu:214523
STRING: 10090.ENSMUSP00000034599
UniGene: Mm.436756
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