Your Good Partner in Biology Research

  1. Home
  2. 抗体
  3. 多克隆抗体
  4. Tmprss4 Antibody

Tmprss4 Antibody

  • 货号：
    CSB-PA844988LA01MO
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Mus musculus (Mouse) Tmprss4 Polyclonal antibody
  • Uniprot No.：
    Q8VCA5
  • 基因名：
    Tmprss4
  • 别名：
    Tmprss4 antibody; Cap2 antibody; Transmembrane protease serine 4 antibody; EC 3.4.21.- antibody; Channel-activating protease 2 antibody; mCAP2 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Mouse
  • 免疫原：
    Recombinant Mouse Transmembrane protease serine 4 protein (52-435AA)
  • 免疫原种属：
    Mus musculus (Mouse)
  • 标记方式：
    Non-conjugated

    本页面中的产品，Tmprss4 Antibody (CSB-PA844988LA01MO)，的标记方式是Non-conjugated。对于Tmprss4 Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA844988LB01MO Tmprss4 Antibody, HRP conjugated ELISA
    FITC CSB-PA844988LC01MO Tmprss4 Antibody, FITC conjugated
    Biotin CSB-PA844988LD01MO Tmprss4 Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Plasma membrane-anchored serine protease that directly induces processing of pro-uPA/PLAU into the active form through proteolytic activity. Seems to be capable of activating ENaC.
  • 基因功能参考文献：
    1. The lung fibrotic response evaluated at 28 days after bleomycin injury was markedly attenuated in the haplodeficient and deficient TMPRSS4 mice. PMID: 29529050
    2. Epithelial Sodium Channel-Mediated Sodium Transport Is Not Dependent on the Membrane-Bound Serine Protease CAP2/Tmprss4 PMID: 26309024
    3. Progression and metastatic potential of several cancers is concordant with an increased expression of TMPRSS4. PMID: 22944691
    4. TMPRSS4 primarily activates ENaC by cleaving basic residues within the tract gammaK173-K186 distal to the furin cleavage site, thereby releasing a previously defined key inhibitory tract encompassing gammaR158-F168 from the gamma-subunit. PMID: 21993886
  • 亚细胞定位：
    Cell membrane; Single-pass type II membrane protein.; [Transmembrane protease serine 4 catalytic chain]: Secreted.
  • 蛋白家族：
    Peptidase S1 family
  • 数据库链接：

    KEGG: mmu:214523

    STRING: 10090.ENSMUSP00000034599

    UniGene: Mm.436756