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UBE2J2 Antibody

  • 货号：
    CSB-PA843143ESR2HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Western blot
      All lanes: Ubiquitin-conjugating enzyme E2 J2 antibody at 5μg/ml
      Lane 1: HepG2 whole cell lysate
      Lane 2: Rat small intestine tissue
      Secondary
      Goat polyclonal to rabbit IgG at 1/10000 dilution
      Predicted band size: 29, 25, 31 kDa
      Observed band size: 29 kDa
    • Immunohistochemistry of paraffin-embedded human breast cancer using CSB-PA843143ESR2HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human liver cancer using CSB-PA843143ESR2HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human lung cancer using CSB-PA843143ESR2HU at dilution of 1:100
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) UBE2J2 Polyclonal antibody
  • Uniprot No.：
    Q8N2K1
  • 基因名：
  • 别名：
    NCUBE-2 antibody; NCUBE2 antibody; Non-canonical ubiquitin-conjugating enzyme 2 antibody; PRO2121 antibody; UB2J2_HUMAN antibody; UBC6 antibody; UBC6 homolog antibody; ube2j2 antibody; Ubiquitin conjugating enzyme 6 antibody; Ubiquitin-conjugating enzyme E2 J2 antibody; Yeast UBC6 homolog antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human, Rat
  • 免疫原：
    Recombinant Human Ubiquitin-conjugating enzyme E2 J2 protein (1-230AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity Purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, WB, IHC
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:5000
    IHC 1:20-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Catalyzes the covalent attachment of ubiquitin to other proteins. Seems to function in the selective degradation of misfolded membrane proteins from the endoplasmic reticulum (ERAD).
  • 基因功能参考文献：
    1. UBE2G2 was crucial for the degradation of various immunoreceptors. UBE2J2, on the other hand, counteracted US2-induced endoplasmic reticulum-associated protein degradation by downregulating TRC8 expression. PMID: 28743740
    2. Endoplasmic reticulum localization and cis-enzymatic activity play a role in regulating the steady state expression of human Ube2J2, ER localization and cis-enzymatic activity play a role in regulating the steady state expression of human Ube2J2. PMID: 25083800
    3. analysis of involvement of E2 enzymes in specifying polyubiquitin chain assembly PMID: 20061386
  • 亚细胞定位：
    Endoplasmic reticulum membrane; Single-pass type IV membrane protein.
  • 蛋白家族：
    Ubiquitin-conjugating enzyme family
  • 数据库链接：

    HGNC: 19268

    KEGG: hsa:118424

    UniGene: Hs.191987