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UBL4A Antibody

  • 货号：
    CSB-PA025499GA01HU
  • 规格：
    ￥3,900
  • 其他：

产品详情

  • Uniprot No.：
    P11441
  • 基因名：
    UBL4A
  • 别名：
    DX254E antibody; DXS254E antibody; G6PD antibody; GDX antibody; OTTHUMP00000061462 antibody; Ubiquitin like 4 antibody; Ubiquitin like 4A antibody; Ubiquitin like protein 4A antibody; Ubiquitin like protein GDX antibody; Ubiquitin-like protein 4A antibody; Ubiquitin-like protein GDX antibody; UBL 4 antibody; UBL 4A antibody; UBL4 antibody; Ubl4a antibody; UBL4A_HUMAN antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse,Rat
  • 免疫原：
    Human UBL4A
  • 免疫原种属：
    Homo sapiens (Human)
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,WB,IHC,IF
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    As part of a cytosolic protein quality control complex, the BAG6/BAT3 complex, maintains misfolded and hydrophobic patches-containing proteins in a soluble state and participates in their proper delivery to the endoplasmic reticulum or alternatively can promote their sorting to the proteasome where they undergo degradation. The BAG6/BAT3 complex is involved in the post-translational delivery of tail-anchored/type II transmembrane proteins to the endoplasmic reticulum membrane. Recruited to ribosomes, it interacts with the transmembrane region of newly synthesized tail-anchored pro...显示更多
  • 基因功能参考文献：
    1. The s identify USP13 as a gp78-associated deubiquitinase that eliminates ubiquitin conjugates from Ubl4A to maintain the functionality of Bag6. PMID: 24424410
    2. Structures of the Sgt2/SGTA dimerization domain with the Get5/UBL4A UBL domain reveal an interaction that forms a conserved dynamic interface. PMID: 23142665
  • 亚细胞定位：
    Cytoplasm, cytosol. Nucleus.
  • 数据库链接：

    HGNC: 12505

    OMIM: 312070

    KEGG: hsa:8266

    STRING: 9606.ENSP00000358674

    UniGene: Hs.76480