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UNC45B Antibody

  • 货号：
    CSB-PA025626GA01HU
  • 规格：
    ￥3,900
  • 其他：

产品详情

  • Uniprot No.：
    Q8IWX7
  • 基因名：
    UNC45B
  • 别名：
    Cardiomyopathy associated 4 antibody; CMYA4 antibody; FLJ38610 antibody; MGC119540 antibody; MGC119541 antibody; OTTHUMP00000163855 antibody; Protein unc 45 homolog B antibody; Protein unc-45 homolog B antibody; SMUNC45 antibody; Striated muscle UNC45 antibody; UN45B_HUMAN antibody; Unc 45 homolog B (C. elegans) antibody; Unc 45 homolog B antibody; UNC 45B antibody; UNC-45B antibody; UNC45 antibody; UNC45B antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse,Rat
  • 免疫原：
    Human UNC45B
  • 免疫原种属：
    Homo sapiens (Human)
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,WB
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Acts as a co-chaperone for HSP90 and is required for proper folding of the myosin motor domain. Plays a role in sarcomere formation during muscle cell development. Is necessary for normal early lens development.
  • 基因功能参考文献：
    1. We have characterized a human UNC45B mutation in a Danish family with autosomal dominant cataract developing in early childhood. PMID: 24549050
    2. temperature-dependent structural changes in the UCS chaperone domain of UNC-45B that occur within a physiologically relevant heat-shock range. PMID: 25436418
  • 相关疾病：
    Cataract 43 (CTRCT43)
  • 亚细胞定位：
    Cytoplasm, cytosol.
  • 组织特异性：
    Expressed in eye lens tissues.
  • 数据库链接：

    HGNC: 14304

    OMIM: 611220

    KEGG: hsa:146862

    STRING: 9606.ENSP00000268876

    UniGene: Hs.379636